SPRYD7

SPRYD7
Identifikatori
Aliasi	SPRYD7
Vanjski ID-jevi	OMIM: 607866 MGI: 1913924 HomoloGene: 10725 GeneCards: SPRYD7
Lokacija gena (čovjek)
Hrom.	Hromosom 13 (čovjek)
Kraj	49,936,490 bp
Lokacija gena (miš)
Hrom.	Hromosom 14 (miš)
Kraj	61,794,335 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ortolozi
	57213
	66674
	ENSG00000123178
	ENSMUSG00000021930
	Q5W111
	Q3TFQ1
	NM_001127482; NM_020456
	NM_025697; NM_001310603
	NP_001120954; NP_065189
	NP_001297532; NP_079973
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

SPRY protein 7 sa domenom (SPRYD7), znan i kao protein 6 delecijske regije hronične limfocitne leukemije (CLLD6) je protein koji je kod ljudi kodiran genom SPRYD7.^[5]^[6]^[7]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 196 aminokiselina, a molekulska težina 21.666 Da.^[8].

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin

N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10	20	30	40	50
MATSVLCCLR	CCRDGGTGHI	PLKEMPAVQL	DTQHMGTDVV	IVKNGRRICG
TGGCLASAPL	HQNKSYFEFK	IQSTGIWGIG	VATQKVNLNQ	IPLGRDMHSL
VMRNDGALYH	NNEEKNRLPA	NSLPQEGDVV	GITYDHVELN	VYLNGKNMHC
PASGIRGTVY	PVVYVDDSAI	LDCQFSEFYH	TPPPGFEKIL	FEQQIF

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000123178 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021930 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mabuchi H, Fujii H, Calin G, Alder H, Negrini M, Rassenti L, Kipps TJ, Bullrich F, Croce CM (Apr 2001). "Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia". Cancer Res. 61 (7): 2870–7. PMID 11306461.
^ Tiazhelova TV, Ivanov DV, Makeeva NV, Kapanadze BI, Nikitin EA, Semov AB, Sangfeldt O, Grander D, Vorob'ev AI, Einhorn S, Iankovskii NK, Baranova AV (Dec 2001). "[Transcription map of the 13q14 region, frequently deleted in B-cell chronic lymphocytic leukemia patients]". Genetika. 37 (11): 1530–7. PMID 11771308.
^ "Entrez Gene: C13orf1 chromosome 13 open reading frame 1".
^ "UniProt, Q5W111". Pristupljeno 5. 8. 2021.

Dopunska literatura

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Mertens D, Wolf S, Schroeter P, et al. (2002). "Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia". Blood. 99 (11): 4116–21. doi:10.1182/blood.V99.11.4116. PMID 12010815.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Gerhard DS, Wagner L, BB Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000123178 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021930 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11306461-5] Mabuchi H, Fujii H, Calin G, Alder H, Negrini M, Rassenti L, Kipps TJ, Bullrich F, Croce CM (Apr 2001). "Cloning and characterization of CLLD6, CLLD7, and CLLD8, novel candidate genes for leukemogenesis at chromosome 13q14, a region commonly deleted in B-cell chronic lymphocytic leukemia". Cancer Res. 61 (7): 2870–7. PMID 11306461.

[pmid11771308-6] Tiazhelova TV, Ivanov DV, Makeeva NV, Kapanadze BI, Nikitin EA, Semov AB, Sangfeldt O, Grander D, Vorob'ev AI, Einhorn S, Iankovskii NK, Baranova AV (Dec 2001). "[Transcription map of the 13q14 region, frequently deleted in B-cell chronic lymphocytic leukemia patients]". Genetika. 37 (11): 1530–7. PMID 11771308.

[entrez-7] "Entrez Gene: C13orf1 chromosome 13 open reading frame 1".

[UniProt-8] "UniProt, Q5W111". Pristupljeno 5. 8. 2021.

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