SFXN1

Siderofleksin-1 jest protein koji je kod ljudi kodiran genom SFXN1 sa hromosoma 5. Prema Nora Kory et al., genski proizvod SFXN1-a ima mitohondrijsku aktivnost serinskog transportera.

SFXN1
Identifikatori
Aliasi	SFXN1
Vanjski ID-jevi	OMIM: 615569 MGI: 2137677 HomoloGene: 41494 GeneCards: SFXN1
Lokacija gena (čovjek) Hrom. Hromosom 5 (čovjek) Bend 5q35.2 Početak 175,477,062 bp Kraj 175,529,742 bp
Lokacija gena (miš) Hrom. Hromosom 13 (miš) Bend 13 B1|13 28.4 cM Početak 54,225,888 bp Kraj 54,262,361 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • ion transmembrane transporter activity • L-serine transmembrane transporter activity • D-serine transmembrane transporter activity Ćelijska komponenta • integral component of membrane • membrana • mitohondrija • mitochondrial membranes • integral component of mitochondrial inner membrane • mitochondrial inner membrane Biološki proces • erythrocyte differentiation • ion transmembrane transport • iron ion homeostasis • iron ion transport • ion transport • transmembrane transport • one-carbon metabolic process • L-serine transport • D-serine transport • serine import into mitochondrion • amino acid transport Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	94081	14057
Ensembl	ENSG00000164466	ENSMUSG00000021474
UniProt	Q9H9B4	Q99JR1
RefSeq (mRNK)	NM_022754 NM_001322977 NM_001322978 NM_001322980 NM_001322981 NM_001322982 NM_001322983	NM_027324
RefSeq (bjelančevina)	NP_001309906 NP_001309907 NP_001309909 NP_001309910 NP_001309911 NP_001309912 NP_073591	NP_081600
Lokacija (UCSC)	Chr 5: 175.48 – 175.53 Mb	Chr 13: 54.23 – 54.26 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 322 aminokiseline, а molekulska težina 35.619 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MSGELPPNIN		IKEPRWDQST		FIGRANHFFT		VTDPRNILLT		NEQLESARKI
VHDYRQGIVP		PGLTENELWR		AKYIYDSAFH		PDTGEKMILI		GRMSAQVPMN
MTITGCMMTF		YRTTPAVLFW		QWINQSFNAV		VNYTNRSGDA		PLTVNELGTA
YVSATTGAVA		TALGLNALTK		HVSPLIGRFV		PFAAVAAANC		INIPLMRQRE
LKVGIPVTDE		NGNRLGESAN		AAKQAITQVV		VSRILMAAPG		MAIPPFIMNT
LEKKAFLKRF		PWMSAPIQVG		LVGFCLVFAT		PLCCALFPQK		SSMSVTSLEA
ELQAKIQESH		PELRRVYFNK		GL

Dopunska literatura

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