RNMTL1

RNK metiltransferoliki protein 1 je enzim koji je kod ljudi kodiran genom RNMTL1.

RNMTL1
Identifikatori
Aliasi	MRM3
Vanjski ID-jevi	OMIM: 612600 MGI: 1914640 HomoloGene: 10033 GeneCards: MRM3
Lokacija gena (čovjek) Hrom. Hromosom 17 (čovjek) Bend 17p13.3 Početak 782,353 bp Kraj 792,509 bp
Lokacija gena (miš) Hrom. Hromosom 11 (miš) Bend 11|11 B5 Početak 76,134,541 bp Kraj 76,141,445 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • RNA methyltransferase activity • aktivnost sa transferazom • GO:0001948, GO:0016582 vezivanje za proteine • rRNA (guanosine-2'-O-)-methyltransferase activity • vezivanje sa RNK • GO:0102674, GO:0102675 methyltransferase activity Ćelijska komponenta • mitochondrial matrix • mitohondrija Biološki proces • rRNA processing • Metilacija • GO:0033168, GO:0036404, GO:1902360 RNA processing • rRNA 2'-O-methylation Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	55178	67390
Ensembl	ENSG00000171861	ENSMUSG00000038046
UniProt	Q9HC36	Q5ND52
RefSeq (mRNK)	NM_018146 NM_001317947	NM_183263
RefSeq (bjelančevina)	NP_001304876 NP_060616	NP_899086
Lokacija (UCSC)	Chr 17: 0.78 – 0.79 Mb	Chr 11: 76.13 – 76.14 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Dužina polipeptidnog lanca je 420 aminokiselina, a molekulska težina 47.020.

Aminokiselinska sekvenca

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10		20		30		40		50
MAALVRPARF		VVRPLLQVVQ		AWDLDARRWV		RALRRSPVKV		VFPSGEVVEQ
KRAPGKQPRK		APSEASAQEQ		REKQPLEESA		SRAPSTWEES		GLRYDKAYPG
DRRLSSVMTI		VKSRPFREKQ		GKILLEGRRL		ISDALKAGAV		PKMFFFSRLE
YLKELPVDKL		KGVSLIKVKF		EDIKDWSDLV		TPQGIMGIFA		KPDHVKMTYP
KTQLQHSLPL		LLICDNLRDP		GNLGTILRSA		AGAGCSKVLL		TKGCVDAWEP
KVLRAGMGAH		FRMPIINNLE		WETVPNYLPP		DTRVYVADNC		GLYAQAEMSN
KASDHGWVCD		QRVMKFHKYE		EEEDVETGAS		QDWLPHVEVQ		SYDSDWTEAP
AAVVIGGETY		GVSLESLQLA		ESTGGKRLLI		PVVPGVDSLN		SAMAASILLF
EGKRQLRGRA		EDLSRDRSYH

Dopunska literatura

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.