Ringoprstni protein 183 je protein koji je kod ljudi kodiran genom RNF183.[5]

RNF183
Identifikatori
AliasiRNF183
Vanjski ID-jeviMGI: 1923322 HomoloGene: 44917 GeneCards: RNF183
Lokacija gena (čovjek)
Hromosom 9 (čovjek)
Hrom.Hromosom 9 (čovjek)[1]
Hromosom 9 (čovjek)
Genomska lokacija za RNF183
Genomska lokacija za RNF183
Bend9q32Početak113,297,093 bp[1]
Kraj113,303,376 bp[1]
Lokacija gena (miš)
Hromosom 4 (miš)
Hrom.Hromosom 4 (miš)[2]
Hromosom 4 (miš)
Genomska lokacija za RNF183
Genomska lokacija za RNF183
Bend4|4 B3Početak62,345,777 bp[2]
Kraj62,353,489 bp[2]
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
vezivanje iona metala
GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity
aktivnost sa transferazom
Ćelijska komponenta membrana
integral component of membrane
Endoplazmatski retikulum
Lizozom
lysosomal membrane
endoplasmic reticulum membrane
Golđijev aparat
integral component of endoplasmic reticulum membrane
cis-Golgi network membrane
Biološki proces protein polyubiquitination
protein ubiquitination
GO:0097285 apoptoza
response to endoplasmic reticulum stress
protein autoubiquitination
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)
NM_145051
NM_001371234
NM_001371235
NM_001371236
NM_001371237

NM_001387568
NM_001387569

NM_153504
NM_001379623
NM_001379624
NM_001379625

RefSeq (bjelančevina)

NP_659488
NP_001358163
NP_001358164
NP_001358165
NP_001358166

NP_705724
NP_001366552
NP_001366553
NP_001366554

Lokacija (UCSC)Chr 9: 113.3 – 113.3 MbChr 4: 62.35 – 62.35 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 192 aminokiseline, а molekulska težina 21.617 Da.[6]

1020304050
MAEQQGRELEAECPVCWNPFNNTFHTPKMLDCCHSFCVECLAHLSLVTPA
RRRLLCPLCRQPTVLASGQPVTDLPTDTAMLALLRLEPHHVILEGHQLCL
KDQPKSRYFLRQPQVYTLDLGPQPGGQTGPPPDTASATVSTPILIPSHHS
LRECFRNPQFRIFAYLMAVILSVTLLLIFSIFWTKQFLWGVG

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000165188 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000063851 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Ring finger protein 183". Pristupljeno 4. 3. 2013.
  6. ^ "UniProt, Q96D59". Pristupljeno 11. 9. 2021.