RERG
RAS-oliki, estrogen-regulirani inhibitor rasta je protein koji je kod ljudi kodiran genom RERG.[5]
RERG, član superporodice RAS GTPaza, inhibira ćelijsku proliferaciju i formiranje tumora (Finlin et al., 2001 PubMed 11533059]).(prema OMIM, mart 2009).
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 199 aminokiselina, a molekulska težina 22.608 Da.[6]
- Simboli
C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MAKSAEVKLA | IFGRAGVGKS | ALVVRFLTKR | FIWEYDPTLE | STYRHQATID | ||||
DEVVSMEILD | TAGQEDTIQR | EGHMRWGEGF | VLVYDITDRG | SFEEVLPLKN | ||||
ILDEIKKPKN | VTLILVGNKA | DLDHSRQVST | EEGEKLATEL | ACAFYECSAC | ||||
TGEGNITEIF | YELCREVRRR | RMVQGKTRRR | SSTTHVKQAI | NKMLTKISS |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000134533 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030222 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: RAS-like, estrogen-regulated, growth inhibitor". Pristupljeno 9. 11. 2012.
- ^ "UniProt, Q96A58". Pristupljeno 14. 8. 2021.
Vanjski linkovi
uredi- PDBe-KB provides an overview of all the structure information available in the PDB for Human Ras-related and estrogen-regulated growth inhibitor (RERG)