RABGAP1
Protein 1 aktivirajuće RAB GTPaze je protein koji je kod ljudi kodiran genom RABGAP1.[5]
Aminokiselinska sekvenca uredi
Dužina polipeptidnog lanca je 1.069aminokiselina, а molekulska težina 121.737 Da.[6]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MDDKASVGKI | SVSSDSVSTL | NSEDFVLVSR | QGDETPSTNN | GSDDEKTGLK | ||||
| IVGNGSEQQL | QKELADVLMD | PPMDDQPGEK | ELVKRSQLDG | EGDGPLSNQL | ||||
| SASSTINPVP | LVGLQKPEMS | LPVKPGQGDS | EASSPFTPVA | DEDSVVFSKL | ||||
| TYLGCASVNA | PRSEVEALRM | MSILRSQCQI | SLDVTLSVPN | VSEGIVRLLD | ||||
| PQTNTEIANY | PIYKILFCVR | GHDGTPESDC | FAFTESHYNA | ELFRIHVFRC | ||||
| EIQEAVSRIL | YSFATAFRRS | AKQTPLSATA | APQTPDSDIF | TFSVSLEIKE | ||||
| DDGKGYFSAV | PKDKDRQCFK | LRQGIDKKIV | IYVQQTTNKE | LAIERCFGLL | ||||
| LSPGKDVRNS | DMHLLDLESM | GKSSDGKSYV | ITGSWNPKSP | HFQVVNEETP | ||||
| KDKVLFMTTA | VDLVITEVQE | PVRFLLETKV | RVCSPNERLF | WPFSKRSTTE | ||||
| NFFLKLKQIK | QRERKNNTDT | LYEVVCLESE | SERERRKTTA | SPSVRLPQSG | ||||
| SQSSVIPSPP | EDDEEEDNDE | PLLSGSGDVS | KECAEKILET | WGELLSKWHL | ||||
| NLNVRPKQLS | SLVRNGVPEA | LRGEVWQLLA | GCHNNDHLVE | KYRILITKES | ||||
| PQDSAITRDI | NRTFPAHDYF | KDTGGDGQDS | LYKICKAYSV | YDEEIGYCQG | ||||
| QSFLAAVLLL | HMPEEQAFSV | LVKIMFDYGL | RELFKQNFED | LHCKFYQLER | ||||
| LMQEYIPDLY | NHFLDISLEA | HMYASQWFLT | LFTAKFPLYM | VFHIIDLLLC | ||||
| EGISVIFNVA | LGLLKTSKDD | LLLTDFEGAL | KFFRVQLPKR | YRSEENAKKL | ||||
| MELACNMKIS | QKKLKKYEKE | YHTMREQQAQ | QEDPIERFER | ENRRLQEANM | ||||
| RLEQENDDLA | HELVTSKIAL | RKDLDNAEEK | ADALNKELLM | TKQKLIDAEE | ||||
| EKRRLEEESA | QLKEMCRREL | DKAESEIKKN | SSIIGDYKQI | CSQLSERLEK | ||||
| QQTANKVEIE | KIRQKVDDCE | RCREFFNKEG | RVKGISSTKE | VLDEDTDEEK | ||||
| ETLKNQLREM | ELELAQTKLQ | LVEAECKIQD | LEHHLGLALN | EVQAAKKTWF | ||||
| NRTLSSIKTA | TGVQGKETC |
Reference uredi
- ^ a b c GRCh38: Ensembl release 89: ENSG00000011454 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035437 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: RAB GTPase activating protein 1".
- ^ "UniProt, Q9Y3P9". Pristupljeno 11. 9. 2021.
Dopunska literatura uredi
- Caratù G, Allegra D, Bimonte M, Schiattarella GG, D'Ambrosio C, Scaloni A, Napolitano M, Russo T, Zambrano N (februar 2007). "Identification of the ligands of protein interaction domains through a functional approach". Molecular & Cellular Proteomics. 6 (2): 333–45. doi:10.1074/mcp.M600289-MCP200. PMID 17124247.
- Echard A, Opdam FJ, de Leeuw HJ, Jollivet F, Savelkoul P, Hendriks W, Voorberg J, Goud B, Fransen JA (novembar 2000). "Alternative splicing of the human Rab6A gene generates two close but functionally different isoforms". Molecular Biology of the Cell. 11 (11): 3819–33. doi:10.1091/mbc.11.11.3819. PMC 15039. PMID 11071909.
- Ishibashi K, Kanno E, Itoh T, Fukuda M (januar 2009). "Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity". Genes to Cells. 14 (1): 41–52. doi:10.1111/j.1365-2443.2008.01251.x. PMID 19077034. S2CID 26454981.
- Opdam FJ, Echard A, Croes HJ, van den Hurk JA, van de Vorstenbosch RA, Ginsel LA, Goud B, Fransen JA (august 2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus". Journal of Cell Science. 113 ( Pt 15) (15): 2725–35. PMID 10893188.
- Cuif MH, Possmayer F, Zander H, Bordes N, Jollivet F, Couedel-Courteille A, Janoueix-Lerosey I, Langsley G, Bornens M, Goud B (april 1999). "Characterization of GAPCenA, a GTPase activating protein for Rab6, part of which associates with the centrosome". The EMBO Journal. 18 (7): 1772–82. doi:10.1093/emboj/18.7.1772. PMC 1171263. PMID 10202141.