ARMC6

(Preusmjereno sa R30923 1)

Ljudski gen ARMC6 kodira protein zvani Armadillo protein 6 sa ponavljanjem.[5][6]

ARMC6
Identifikatori
AliasiARMC6
Vanjski ID-jeviMGI: 1924063 HomoloGene: 14121 GeneCards: ARMC6
Lokacija gena (čovjek)
Hromosom 19 (čovjek)
Hrom.Hromosom 19 (čovjek)[1]
Hromosom 19 (čovjek)
Genomska lokacija za ARMC6
Genomska lokacija za ARMC6
Bend19p13.11Početak19,033,575 bp[1]
Kraj19,060,311 bp[1]
Lokacija gena (miš)
Hromosom 8 (miš)
Hrom.Hromosom 8 (miš)[2]
Hromosom 8 (miš)
Genomska lokacija za ARMC6
Genomska lokacija za ARMC6
Bend8|8 B3.3Početak70,672,822 bp[2]
Kraj70,687,116 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001199196
NM_033415

NM_133972

RefSeq (bjelančevina)

NP_001186125
NP_219483

NP_598733

Lokacija (UCSC)Chr 19: 19.03 – 19.06 MbChr 8: 70.67 – 70.69 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Funkcija proteinskog proizvoda ovog gena nije utvrđena. Srodni protein kod miša sugerira da ovaj protein ima konzerviranu funkciju.[6]

Za protein je karakteristično prisustvo ponavljanja Amadrillo u njegovom aminokiselinskoj sekvenci. Bolesti povezane sa ARMC6 uključuju rak gušterače i pankreatitis.

Aminokiselinska sekvenca

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Simboli
1020304050
MSERCCSRYSSGASIGCTPTSTQAKMVSKRIAQETFDAAVRENIEEFAMG
PEEAVKEAVEQFESQGVDLSNIVKTAPKVSADGSQEPTHDILQMLSDLQE
SVASSRPQEVSAYLTRFCDQCKQDKACRFLAAQKGAYPIIFTAWKLATAG
DQGLLLQSLNALSVLTDGQPDLLDAQGLQLLVATLTQNADEADLTCSGIR
CVRHACLKHEQNRQDLVKAGVLPLLTGAITHHGHHTDVVREACWALRVMT
FDDDIRVPFGHAHNHAKMIVQENKGLKVLIEATKAFLDNPGILSELCGTL
SRLAIRNEFCQEVVDLGGLSILVSLLADCNDHQMRDQSGVQELVKQVLST
LRAIAGNDDVKDAIVRAGGTESIVAAMTQHLTSPQVCEQSCAALCFLALR
KPDNSRIIVEGGGAVAALQAMKAHPQKAGVQKQACMLIRNLVAHGQAFSK
PILDLGAEALIMQARSAHRDCEDVAKAALRDLGCHVELRELWTGQRGNLA
P

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105676 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002343 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ a b "Entrez Gene: ARMC6 armadillo repeat containing 6".
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Further reading

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