Prolinom bogati protein 5 je protein koji je kod ljudi kodiran genom PRR5L.[5]

PRR5L
Identifikatori
AliasiPRR5L
Vanjski ID-jeviOMIM: 611728 MGI: 1919696 HomoloGene: 11753 GeneCards: PRR5L
Lokacija gena (čovjek)
Hromosom 11 (čovjek)
Hrom.Hromosom 11 (čovjek)[1]
Hromosom 11 (čovjek)
Genomska lokacija za PRR5L
Genomska lokacija za PRR5L
Bend11p13-p12Početak36,296,288 bp[1]
Kraj36,465,204 bp[1]
Lokacija gena (miš)
Hromosom 2 (miš)
Hrom.Hromosom 2 (miš)[2]
Hromosom 2 (miš)
Genomska lokacija za PRR5L
Genomska lokacija za PRR5L
Bend2|2 E2Početak101,544,630 bp[2]
Kraj101,713,372 bp[2]
Ontologija gena
Molekularna funkcija ubiquitin protein ligase binding
GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta TORC2 complex
Biološki proces TORC2 signaling
GO:0033128 negative regulation of protein phosphorylation
positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of signal transduction
positive regulation of protein phosphorylation
regulation of fibroblast migration
cellular response to oxidative stress
positive regulation of mRNA catabolic process
positive regulation of intracellular protein transport
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_024841
NM_001160167
NM_001160168
NM_001160169

NM_001083810
NM_001110849
NM_175181
NM_001355625

RefSeq (bjelančevina)

NP_001153639
NP_001153640
NP_001153641
NP_079117

NP_001077279
NP_001104319
NP_780390
NP_001342554

Lokacija (UCSC)Chr 11: 36.3 – 36.47 MbChr 2: 101.54 – 101.71 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 368 aminokiselina, a molekulska težina 40.836 Da.[6]

1020304050
MTRGFAPILPVEFHKMGSFRRPRPRFMSSPVLSDLPRFQAARQALQLSSS
SAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQ
LLAKGLFFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQ
ELTIRQISLLGFRDLVLLKVKLGDLLLLAQSKLPSSIVQMLLILQSVHEP
TGPSESYLQLEELVKQVVSPFLGISGDRSFSGPTYTLARRHSRVRPKVTV
LNYASPITAVSRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQ
LLAMATMMHSGLGEEASSENKCLLLPPSFPPPHRQCSSEPNITDNPDGLE
EGARGSQEGSELNCASLS

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135362 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032841 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Proline rich 5 like". Pristupljeno 17. 3. 2017.
  6. ^ "UniProt, Q6MZQ0". Pristupljeno 25. 8. 2021.

Dopunska literatura

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