Regulacijska podjedinica 17 protein-fosfataze 1 je protein koji je kod ljudi kodiran genom PPP1R17'.[5][6][7]

PPP1R17
Identifikatori
AliasiPPP1R17
Vanjski ID-jeviOMIM: 604088 MGI: 1333876 HomoloGene: 4849 GeneCards: PPP1R17
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za PPP1R17
Genomska lokacija za PPP1R17
Bend7p14.3Početak31,687,215 bp[1]
Kraj31,708,455 bp[1]
Lokacija gena (miš)
Hromosom 6 (miš)
Hrom.Hromosom 6 (miš)[2]
Hromosom 6 (miš)
Genomska lokacija za PPP1R17
Genomska lokacija za PPP1R17
Bend6 B3|6 27.65 cMPočetak55,994,482 bp[2]
Kraj56,009,674 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija protein phosphatase inhibitor activity
protein serine/threonine phosphatase inhibitor activity
phosphatase inhibitor activity
Ćelijska komponenta ćelijska komponenta
nukleoplazma
Biološki proces regulation of phosphatase activity
central nervous system development
GO:0007243 intracellular signal transduction
GO:0048553 negative regulation of catalytic activity
negative regulation of phosphoprotein phosphatase activity
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001145123
NM_006658

NM_011153

RefSeq (bjelančevina)

NP_001138595
NP_006649

NP_035283

Lokacija (UCSC)Chr 7: 31.69 – 31.71 MbChr 6: 55.99 – 56.01 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 155 aminokiselina, а molekulska težina 17.866 Da.[8]

1020304050
MMSTEQMQPLELSEDRLDKLDPRCSHLDDLSDQFIKDCDLKKKPRKGKNV
QATLNVESDQKKPRRKDTPALHIPPFIPGVFSEHLIKRYDVQERHPKGKM
IPVLHNTDLEQKKPRRKDTPALHMSPFAAGVTLLRDERPKAIVEDDEKDG
DKIAI

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106341 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002930 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Endo S, Suzuki M, Sumi M, Nairn AC, Morita R, Yamakawa K, Greengard P, Ito M (Mar 1999). "Molecular identification of human G-substrate, a possible downstream component of the cGMP-dependent protein kinase cascade in cerebellar Purkinje cells". Proceedings of the National Academy of Sciences of the United States of America. 96 (5): 2467–72. doi:10.1073/pnas.96.5.2467. PMC 26808. PMID 10051666.
  6. ^ Hall KU, Collins SP, Gamm DM, Massa E, DePaoli-Roach AA, Uhler MD (Feb 1999). "Phosphorylation-dependent inhibition of protein phosphatase-1 by G-substrate. A Purkinje cell substrate of the cyclic GMP-dependent protein kinase". The Journal of Biological Chemistry. 274 (6): 3485–95. doi:10.1074/jbc.274.6.3485. PMID 9920894.
  7. ^ "Entrez Gene: C7orf16 chromosome 7 open reading frame 16".
  8. ^ "UniProt, O96001" (jezik: engleski). Pristupljeno 28. 9. 2021.

Dopunska literatura

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Vanjski linkovi

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