PDAP1

Toplotno i kiselinsko-stabilni fosfoprotein od 28 kDa je protein koji je kod ljudi kodiran genom PDAP1.

PDAP1
Identifikatori
Aliasi	PDAP1
Vanjski ID-jevi	OMIM: 607075 MGI: 2448536 HomoloGene: 8927 GeneCards: PDAP1
Lokacija gena (čovjek) Hrom. Hromosom 7 (čovjek) Bend 7q22.1 Početak 99,392,048 bp Kraj 99,408,597 bp
Lokacija gena (miš) Hrom. Hromosom 5 (miš) Bend 5|5 G2 Početak 145,065,579 bp Kraj 145,077,048 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • vezivanje sa RNK Ćelijska komponenta • extracellular region • ficolin-1-rich granule lumen • citosol • ćelijska membrana Biološki proces • GO:0072468 Transdukcija signala • Ćelijska proliferacija • neutrophil degranulation Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	11333	231887
Ensembl	ENSG00000106244	ENSMUSG00000029623
UniProt	Q13442	Q3UHX2
RefSeq (mRNK)	NM_014891	NM_001033313
RefSeq (bjelančevina)	NP_055706	NP_001028485
Lokacija (UCSC)	Chr 7: 99.39 – 99.41 Mb	Chr 5: 145.07 – 145.08 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 181 aminokiselina, а molekulska težina 20.630 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MPKGGRKGGH		KGRARQYTSP		EEIDAQLQAE		KQKAREEEEQ		KEGGDGAAGD
PKKEKKSLDS		DESEDEEDDY		QQKRKGVEGL		IDIENPNRVA		QTTKKVTQLD
LDGPKELSRR		EREEIEKQKA		KERYMKMHLA		GKTEQAKADL		ARLAIIRKQR
EEAARKKEEE		RKAKDDATLS		GKRMQSLSLN		K

Dopunska literatura

• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
• LaRochelle WJ, Jeffers M, McDonald WF, et al. (2001). "PDGF-D, a new protease-activated growth factor". Nat. Cell Biol. 3 (5): 517–21. doi:10.1038/35074593. PMID 11331882. S2CID 19633551.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.