Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 2.034 aminokiseline, a molekulska težina 222.039 Da.[6]
| 10 | | 20 | | 30 | | 40 | | 50 |
|---|
| MGSQVLQILR | | QGVWASLTGG | | WFFDPHQSTF | | SNCFHLYVWI | | FLLIFPFLLY |
| MVLPPSLMVA | | GVYCLVVAVI | | FATIKTVNYR | | LHAMFDQGEI | | VEKRSSTMGE |
| LEEEPAQGDS | | NPPRDPGVEM | | TVFRKVSSTP | | PVRCSSQHSV | | FGFNQVSELL |
| PRMEDSGPLR | | DIKELVREQG | | SNNVIVTSAD | | REMLKLSSQE | | KLIGDLPQTP |
| PGAVPDPSLA | | STDSSEPSPL | | AGDGAPWSGS | | SMADTPMSPL | | LKGSLSQELS |
| KSFLTLTQPD | | RALVRTSSRR | | EQRRGAGGYQ | | PLDRRGSGEP | | TPQKAGSSDS |
| CFSGTDRETL | | SSFKSEKTNS | | THLDSPPGGP | | APEGSDTDPP | | SEAELPASPD |
| AGVPSDDTLR | | SFDTVIGAGT | | PPGLAEPLLV | | VRPKDLALLR | | PSKRQPPLRR |
| HSPPGRAPRR | | PLLEGGGFFE | | DEDTSEGSEL | | SPASSLRSQR | | RYSTDSSSST |
| SCYSPESSRG | | AAGGPRKRRA | | PHGAEEGTAV | | PPKRPYGTQR | | TPSTASAKTH |
| ARVLSMDGAG | | GDVLRPPLAG | | CKAELEAQVG | | VEQAASEPVV | | LPAEARRGPA |
| ANQPGWRGEL | | QEEGAVGGAA | | EETGRRDRSS | | SVRRTQAIRR | | RHNAGSNPTP |
| PASVMGSPPS | | SLQEAQRGRA | | ASHSRALTLP | | SALHFASSLL | | LTRAGANVHE |
| ACTFDDTSEG | | AVHYFYDESG | | VRRSYTFGLA | | GGGYENPVGQ | | QGEQTANGAW |
| DRHSHSSSFH | | SADVPEATGG | | LNLLQPRPVV | | LQGMQVRRVP | | LEIPEEQTLM |
| EEAPPRAQHS | | YKYWLLPGRW | | TSVRYERLAL | | LALLDRTRGV | | LENIFGVGLS |
| SLVAFLGYLL | | LLKGFFTDIW | | VFQFCLVIAS | | CQYSLLKSVQ | | PDAASPMHGH |
| NWVIAYSRPV | | YFCICCLLIW | | LLDALGSAQP | | FPPVSLYGLT | | LFSASFFFCA |
| RDVATVFTLC | | FPFVFLLGLL | | PQVNTCLMYL | | LEQIDMHGFG | | GTAATSPLTA |
| VFSLSRSLLA | | AALLYGFCLG | | AIKTPWPEQH | | VPVLFSVFCG | | LLVALSYHLS |
| RQSSDPTVLW | | SLIRSKLFPE | | LEERSLETAR | | AEPPDPLPDK | | MRQSVREVLH |
| SDLVMCVVIA | | VLTFAISAST | | VFIALKSVLG | | FVLYALAGAV | | GFFTHYLLPQ |
| LRKQLPWFCL | | SQPVLKPLEY | | SQYEVRGAAQ | | VMWFEKLYAG | | LQCVEKYLIY |
| PAVVLNALTV | | DAHTVVSHPD | | KYCFYCRALL | | MTVAGLKLLR | | SAFCCPPQQY |
| LTLAFTVLLF | | HFDYPRLSQG | | FLLDYFLMSL | | LCSKLWDLLY | | KLRFVLTYIA |
| PWQITWGSAF | | HAFAQPFAVP | | HSAMLFVQAL | | LSGLFSTPLN | | PLLGSAVFIM |
| SYARPLKFWE | | RDYNTKRVDH | | SNTRLVTQLD | | RNPGADDNNL | | NSIFYEHLTR |
| SLQHTLCGDL | | VLGRWGNYGP | | GDCFVLASDY | | LNALVHLIEV | | GNGLVTFQLR |
| GLEFRGTYCQ | | QREVEAITEG | | VEEDEGCCCC | | EPGHLPRVLS | | FNAAFGQRWL |
| AWEVTASKYV | | LEGYSISDNN | | AASMLQVFDL | | RKILITYYVK | | SIIYYVSRSP |
| KLEVWLSHEG | | ITAALRPVRV | | PGYADSDPTF | | SLSVDEDYDL | | RLSGLSLPSF |
| CAVHLEWIQY | | CASRRSQPVD | | QDWNSPLVTL | | CFGLCVLGRR | | ALGTASHSMS |
| ASLEPFLYGL | | HALFKGDFRI | | TSPRDEWVFA | | DMDLLHRVVA | | PGVRMALKLH |
| QDHFTSPDEY | | EEPAALYDAI | | AANEERLVIS | | HEGDPAWRSA | | ILSNTPSLLA |
| LRHVLDDASD | | EYKIIMLNRR | | HLSFRVIKVN | | RECVRGLWAG | | QQQELVFLRN |
| RNPERGSIQN | | AKQALRNMIN | | SSCDQPLGYP | | IYVSPLTTSL | | AGSHPQLRAL |
| WGGPISLGAI | | AHWLLRTWER | | LHKGCGAGCN | | SGGNVDDSDC | | SGGGGLTSLS |
| NNPPVAHPTP | | ENTAGNGDQP | | LPPGPGWGPR | | SSLSGSGDGR | | PPPLLQWPPP |
| RLPGPPPASP | | IPTEGPRTSR | | PPGPGLLSSE | | GPSGKWSLGG | | RKGLGGSDGE |
| PASGSPKGGT | | PKSQAPLDLS | | LSLSLSLSPD | | VSTEASPPRA | | SQDIPCLDSS |
| APESGTPMGA | | LGDWPAPIEE | | RESPAAQPLL | | EHQY |
Dopunska literatura
uredi
- Mavaddat N, Dunning AM, Ponder BA, Easton DF, Pharoah PD (2009). "Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer". Cancer Epidemiol. Biomarkers Prev. 18 (1): 255–259. doi:10.1158/1055-9965.EPI-08-0704. PMC 2655077. PMID 19124506.
- Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–642. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
