P53AIP1

P53AIP1
Identifikatori
Aliasi	TP53AIP1
Vanjski ID-jevi	OMIM: 605426 HomoloGene: 137360 GeneCards: TP53AIP1
Lokacija gena (čovjek)
Hrom.	Hromosom 11 (čovjek)
Kraj	128,943,399 bp
Obrazac RNK ekspresije
	; ;
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• molekularna funkcija;
Ćelijska komponenta	• mitohondrija; • mitochondrial matrix;
Biološki proces	• GO:0097285 apoptoza; • regulation of apoptotic process;
	Izvori:Amigo / QuickGO
Ortolozi
	63970
	n/a
	ENSG00000120471
	n/a
	Q9HCN2
	n/a
	NM_022112; NM_001195194; NM_001195195; NM_001251964
	n/a
	NP_001182123; NP_001182124; NP_001238893; NP_071395
	n/a
	Wikipodaci
Pogledaj/uredi – čovjek

p53-regulirani apoptoza-inducirajući protein 1 je protein koji je kod ljudi kodiran genom TP53AIP1.^[3]^[4]^[5]

Aminokiselinska sekvenca uredi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120471 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Oda K, Arakawa H, Tanaka T, Matsuda K, Tanikawa C, Mori T, Nishimori H, Tamai K, Tokino T, Nakamura Y, Taya Y (Oct 2000). "p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53". Cell. 102 (6): 849–62. doi:10.1016/S0092-8674(00)00073-8. PMID 11030628. S2CID 3051667.
^ Matsuda K, Yoshida K, Taya Y, Nakamura K, Nakamura Y, Arakawa H (maj 2002). "p53AIP1 regulates the mitochondrial apoptotic pathway". Cancer Res. 62 (10): 2883–9. PMID 12019168.
^ "Entrez Gene: P53AIP1 p53-regulated apoptosis-inducing protein 1".
^ "UniProt, Q9HCN2". Pristupljeno 25. 8. 2021.

Strano S, Monti O, Pediconi N, et al. (2005). "The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage". Mol. Cell. 18 (4): 447–59. doi:10.1016/j.molcel.2005.04.008. PMID 15893728.
Wesierska-Gadek J, Gueorguieva M, Horky M (2005). "Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells". Mol. Cancer Ther. 4 (1): 113–24. PMID 15657359.
Chan KT, Lung ML (2004). "Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line". Cancer Chemother. Pharmacol. 53 (6): 519–26. doi:10.1007/s00280-004-0767-4. PMID 15004724. S2CID 13125987.
Kövesi G, Szende B (2004). "Changes in apoptosis and mitotic index, p53 and Ki67 expression in various types of oral leukoplakia". Oncology. 65 (4): 331–6. doi:10.1159/000074646. PMID 14707453. S2CID 19136670.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Venter JC, Adams MD, Myers EW, et al. (2001). "The sequence of the human genome". Science. 291 (5507): 1304–51. doi:10.1126/science.1058040. PMID 11181995.