Homolog proteina MON2 je protein koji je kod ljudi kodiran genom MON2.[5][6]

MON2
Identifikatori
AliasiMON2
Vanjski ID-jeviOMIM: 616822 MGI: 1914324 HomoloGene: 44309 GeneCards: MON2
Lokacija gena (čovjek)
Hromosom 12 (čovjek)
Hrom.Hromosom 12 (čovjek)[1]
Hromosom 12 (čovjek)
Genomska lokacija za MON2
Genomska lokacija za MON2
Bend12q14.1Početak62,466,817 bp[1]
Kraj62,600,476 bp[1]
Lokacija gena (miš)
Hromosom 10 (miš)
Hrom.Hromosom 10 (miš)[2]
Hromosom 10 (miš)
Genomska lokacija za MON2
Genomska lokacija za MON2
Bend10|10 D2Početak122,827,965 bp[2]
Kraj122,912,410 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta Egzosom
citosol
Biološki proces protein transport
Golgi to endosome transport
GO:0015915 transport
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001278469
NM_001278470
NM_001278471
NM_001278472
NM_015026

NM_001163024
NM_001163025
NM_153395

RefSeq (bjelančevina)
NP_001265398
NP_001265399
NP_001265400
NP_001265401
NP_055841

NP_001265400.1

NP_001156496
NP_001156497
NP_700444

Lokacija (UCSC)Chr 12: 62.47 – 62.6 MbChr 10: 122.83 – 122.91 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 1.717 aminokiselina, a molekulska težina 190.359 Da.[7].

1020304050
MSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIA
ARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVS
ETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLC
FRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGN
SNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELL
ESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPA
PVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQW
LRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSL
FLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIGGGVTLLPAFEYRGT
WIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGIT
SMIEGELGELETECQTTTEEGSSPTQSTEQQDLQSTSDQMDKEIVSRAVW
EEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTS
RDAFITAICKGSLPPHYALTVLNTTTAATLSNKSYSVQGQSVMMISPSSE
SHQQVVAVGQPLAVQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQL
VLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPVISNIL
SRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLE
TGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFN
HDPPLSQNQRLQLLLLNPLKEMSNINHPDIRLKQLECVLQILQSQGDSLG
PGWPLVLGVMGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVD
VAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQ
AEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFS
TIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILI
HHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHI
QSAALSKNNEVSLAALKSFQEILQIVSPVRDSDKPETPPVVNVPVPVLIG
PISGMSRPFVRTDSIGEKLGRYSSSEPPIVTDELEDLNLWWAAWNTWYRI
GSESTKPPITFDKLTFIPSQPFLTALIQIFPALYQHIKTGFNMDDLQKLG
VILHSAISVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGP
ENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAE
WVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRVPLSLK
YSCPSESTWKLAVSSLLRVLSIGLPVARQHASSGKFDSMWPELANTFEDF
LFTKSIPPDNLSIQEFQRNENIDVEVVQLISNEILPYANFIPKEFVGQIM
TMLNKGSIHSQSSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQE
GYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVS
TLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSEVCSALKEALVP
FKDFMQPPASRVQNGES
Simboli

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000061987 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034602 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gillingham AK, Whyte JR, Panic B, Munro S (Jan 2006). "Mon2, a relative of large Arf exchange factors, recruits Dop1 to the Golgi apparatus". J Biol Chem. 281 (4): 2273–80. doi:10.1074/jbc.M510176200. PMID 16301316.
  6. ^ "Entrez Gene: MON2 MON2 homolog (S. cerevisiae)".
  7. ^ "UniProt, Q7Z3U7". Pristupljeno 12. 8. 2021.

Dopunska literatura

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