Melanomski inhibitorno aktivni protein 2 je protein koji je kod ljudi kodiran genom MIA2.[3][4]

MIA2
Identifikatori
AliasiMIA2
Vanjski ID-jeviMGI: 2159614 HomoloGene: 137655 GeneCards: MIA2
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta endoplasmic reticulum membrane
Endoplazmatski retikulum
integral component of membrane
membrana
endoplasmic reticulum exit site
Biološki proces lipoprotein transport
vesicle cargo loading
endoplasmic reticulum to Golgi vesicle-mediated transport
protein secretion
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

n/a

NM_177321

RefSeq (bjelančevina)
NP_001234917
NP_001234918
NP_001234919
NP_001316143
NP_001341066

NP_001341067
NP_001341068
NP_001341069
NP_001341070
NP_001341071
NP_001341072
NP_001341073
NP_001341074
NP_001341075
NP_001341076
NP_001341077
NP_001341078
NP_001341079
NP_001341080
NP_001341081
NP_001341082
NP_001341083
NP_001341084
NP_001341085
NP_001341086
NP_005921
NP_473365
NP_976229
NP_976230
NP_976231

NP_001158725
NP_001158726
NP_001315976
NP_666146
NP_001355768

Lokacija (UCSC)n/an/a
PubMed pretraga[1][2]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 1.412 aminokiselina, a molekulska težina 159.836 Da [5].

Simboli
1020304050
MAKFGVHRILLLAISLTKCLESTKLLADLKKCGDLECEALINRVSAMRDY
RGPDCRYLNFTKGEEISVYVKLAGEREDLWAGSKGKEFGYFPRDAVQIEE
VFISEEIQMSTKESDFLCLLGVSYTFDNEDSELNGDYGENIYPYEEDKDE
KSSIYESDFQIEPGFYATYESTLFEDQVPALEAPEDIGSTSESKDWEEVV
VESMEQDRIPEVHVPPSSAVSGVKEWFGLGGEQAEEKAFESVIEPVQESS
FRSRKIAVEDENDLEELNNGEPQTEHQQESESEIDSVPKTQSELASESEH
IPKPQSTGWFGGGFTSYLGFGDEDTGLELIAEESNPPLQDFPNSISSDKE
ATVPCTEILTEKKDTITNDSLSLKPSWFDFGFAILGFAYAKEDKIMLDDR
KNEEDGGADEHEHPLTSELDPEKEQEIETIKIIETEDQIDKKPVSEKTDE
SDTIPYLKKFLYNFDNPWNFQNIPKETELPFPKQILDQNNVIENEETGEF
SIDNYPTDNTKVMIFKSSYSLSDMVSNIELPTRIHEEVYFEPSSSKDSDE
NSKPSVDTEGPALVEIDRSVENTLLNSQMVSTDNSLSSQNYISQKEDASE
FQILKYLFQIDVYDFMNSAFSPIVILTERVVAALPEGMRPDSNLYGFPWE
LVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKL
LEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEATCEKLNRSNSELE
DEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKM
TFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQ
KVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLE
LEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSE
VDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQEN
EMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEEL
ERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETE
LKFELLEKDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLE
GPLRLSPLLPGGGGRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDT
GSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRS
FNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGPGFV
PPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPG
PPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNE
PATEHPEPQQET

Reference

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  1. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Bosserhoff AK, Moser M, Scholmerich J, Buettner R, Hellerbrand C (Apr 2003). "Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes". J Biol Chem. 278 (17): 15225–31. doi:10.1074/jbc.M212639200. PMID 12586826.
  4. ^ "Entrez Gene: MIA2 melanoma inhibitory activity 2".
  5. ^ "UniProt, Q96PC5". Pristupljeno 27. 7. 2021.

Dopunska literatura

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