Leucinom bogati protein 17 sa ponavljanjem je protein koji je kod ljudi kodiran genom LRRC17.[5][6][7]

LRRC17
Identifikatori
AliasiLRRC17
Vanjski ID-jeviMGI: 1921761 HomoloGene: 55929 GeneCards: LRRC17
Lokacija gena (čovjek)
Hromosom 7 (čovjek)
Hrom.Hromosom 7 (čovjek)[1]
Hromosom 7 (čovjek)
Genomska lokacija za LRRC17
Genomska lokacija za LRRC17
Bend7q22.1Početak102,913,000 bp[1]
Kraj102,945,111 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za LRRC17
Genomska lokacija za LRRC17
Bend5|5 A3Početak21,748,557 bp[2]
Kraj21,780,902 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001031692
NM_005824

NM_028977

RefSeq (bjelančevina)

NP_001026862
NP_005815

NP_083253

Lokacija (UCSC)Chr 7: 102.91 – 102.95 MbChr 5: 21.75 – 21.78 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 441 aminokiselina, а molekulska težina 51.800 Da.[8]

1020304050
MRVVTIVILLCFCKAAELRKASPGSVRSRVNHGRAGGGRRGSNPVKRYAP
GLPCDVYTYLHEKYLDCQERKLVYVLPGWPQDLLHMLLARNKIRTLKNNM
FSKFKKLKSLDLQQNEISKIESEAFFGLNKLTTLLLQHNQIKVLTEEVFI
YTPLLSYLRLYDNPWHCTCEIETLISMLQIPRNRNLGNYAKCESPQEQKN
KKLRQIKSEQLCNEEEKEQLDPKPQVSGRPPVIKPEVDSTFCHNYVFPIQ
TLDCKRKELKKVPNNIPPDIVKLDLSYNKINQLRPKEFEDVHELKKLNLS
SNGIEFIDPAAFLGLTHLEELDLSNNSLQNFDYGVLEDLYFLKLLWLRDN
PWRCDYNIHYLYYWLKHHYNVHFNGLECKTPEEYKGWSVGKYIRSYYEEC
PKDKLPAYPESFDQDTEDDEWEKKHRDHTAKKQSVIITIVG

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128606 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039883 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kim D, LaQuaglia MP, Yang SY (Jan 1997). "A cDNA encoding a putative 37 kDa leucine-rich repeat (LRR) protein, p37NB, isolated from S-type neuroblastoma cell has a differential tissue distribution". Biochim Biophys Acta. 1309 (3): 183–8. doi:10.1016/s0167-4781(96)00158-3. PMID 8982252.
  6. ^ Kim T, Kim K, Lee SH, So HS, Lee J, Kim N, Choi Y (maj 2009). "Identification of LRRc17 as a Negative Regulator of Receptor Activator of NF-κB Ligand (RANKL)-induced Osteoclast Differentiation". J Biol Chem. 284 (22): 15308–16. doi:10.1074/jbc.M807722200. PMC 2685711. PMID 19336404.
  7. ^ "Entrez Gene: LRRC17 leucine rich repeat containing 17".
  8. ^ "UniProt, Q8N6Y2" (jezik: engleski). Pristupljeno 26. 9. 2021.

Dopunska literatura

uredi

Vanjski linkovi

uredi

LRRC17 detalji ljudskog genoma u UCSC Genome Browser.

{