Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 797 aminokiselina , а molekulska težina 89.387 Da .[ 6]
10 20 30 40 50 MYLETRRAIF VFWIFLQVQG TKDISINIYH SETKDIDNPP RNETTESTEK MYKMSTMRRI FDLAKHRTKR SAFFPTGVKV CPQESMKQIL DSLQAYYRLR VCQEAVWEAY RIFLDRIPDT GEYQDWVSIC QQETFCLFDI GKNFSNSQEH LDLLQQRIKQ RSFPDRKDEI SAEKTLGEPG ETIVISTDVA NVSLGPFPLT PDDTLLNEIL DNTLNDTKMP TTERETEFAV LEEQRVELSV SLVNQKFKAE LADSQSPYYQ ELAGKSQLQM QKIFKKLPGF KKIHVLGFRP KKEKDGSSST EMQLTAIFKR HSAEAKSPAS DLLSFDSNKI ESEEVYHGTM EEDKQPEIYL TATDLKRLIS KALEEEQSLD VGTIQFTDEI AGSLPAFGPD TQSELPTSFA VITEDATLSP ELPPVEPQLE TVDGAEHGLP DTSWSPPAMA STSLSEAPPF FMASSIFSLT DQGTTDTMAT DQTMLVPGLT IPTSDYSAIS QLALGISHPP ASSDDSRSSA GGEDMVRHLD EMDLSDTPAP SEVPELSEYV SVPDHFLEDT TPVSALQYIT TSSMTIAPKG RELVVFFSLR VANMAFSNDL FNKSSLEYRA LEQQFTQLLV PYLRSNLTGF KQLEILNFRN GSVIVNSKMK FAKSVPYNLT KAVHGVLEDF RSAAAQQLHL EIDSYSLNIE PADQADPCKF LACGEFAQCV KNERTEEAEC RCKPGYDSQG SLDGLEPGLC GPGTKECEVL QGKGAPCRLP DHSENQAYKT SVKKFQNQQN NKVISKRNSE LLTVEYEEFN HQDWEGN
Dopunska literatura
uredi
Felbor U, Gehrig A, Sauer CG, et al. (1998). "Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: a candidate for 6q-linked retinopathies". Cytogenet. Cell Genet . 81 (1): 12–7. doi :10.1159/000015001 . PMID 9691169 . S2CID 46766267 . Gehrig A, Felbor U, Kelsell RE, et al. (1998). "Assessment of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene localised to 6q13-q15 in autosomal dominant Stargardt-like disease (ADSTGD), progressive bifocal chorioretinal atrophy (PBCRA), and North Carolina macular dystrophy (MCDR1)" . J. Med. Genet . 35 (8): 641–5. doi :10.1136/jmg.35.8.641 . PMC 1051388 PMID 9719369 . Acharya S, Rayborn ME, Hollyfield JG (1998). "Characterization of SPACR, a sialoprotein associated with cones and rods present in the interphotoreceptor matrix of the human retina: immunological and lectin binding analysis" . Glycobiology . 8 (10): 997–1006. doi :10.1093/glycob/8.10.997 PMID 9719680 . Acharya S, Rodriguez IR, Moreira EF, et al. (1998). "SPACR, a novel interphotoreceptor matrix glycoprotein in human retina that interacts with hyaluronan" . J. Biol. Chem . 273 (47): 31599–606. doi :10.1074/jbc.273.47.31599 PMID 9813076 . Kuehn MH, Hageman GS (2000). "Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan". Matrix Biol . 18 (5): 509–18. doi :10.1016/S0945-053X(99)00043-8 . PMID 10601738 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6" . Nature . 425 (6960): 805–11. Bibcode :2003Natur.425..805M . doi :10.1038/nature02055 PMID 14574404 . van Lith-Verhoeven JJ, Hoyng CB, van den Helm B, et al. (2004). "The benign concentric annular macular dystrophy locus maps to 6p12.3-q16" . Invest. Ophthalmol. Vis. Sci . 45 (1): 30–5. doi :10.1167/iovs.03-0392 PMID 14691150 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Abd El-Aziz MM, El-Ashry MF, Barragan I, et al. (2006). "Molecular genetic analysis of two functional candidate genes in the autosomal recessive retinitis pigmentosa, RP25, locus". Curr. Eye Res . 30 (12): 1081–7. doi :10.1080/02713680500351039 . PMID 16354621 . S2CID 26204316 . 
