Homolog međuflagelskog transportnog proteina 46 je protein koji je kod ljudi kodiran genom IFT46.[5][6][7]

IFT46
Identifikatori
AliasiIFT46
Vanjski ID-jeviMGI: 1923818 HomoloGene: 10596 GeneCards: IFT46
Lokacija gena (čovjek)
Hromosom 11 (čovjek)
Hrom.Hromosom 11 (čovjek)[1]
Hromosom 11 (čovjek)
Genomska lokacija za IFT46
Genomska lokacija za IFT46
Bend11q23.3Početak118,544,528 bp[1]
Kraj118,572,970 bp[1]
Lokacija gena (miš)
Hromosom 9 (miš)
Hrom.Hromosom 9 (miš)[2]
Hromosom 9 (miš)
Genomska lokacija za IFT46
Genomska lokacija za IFT46
Bend9|9 A5.2Početak44,679,205 bp[2]
Kraj44,704,744 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija protein C-terminus binding
molekularna funkcija
GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta citoplazma
intraciliary transport particle B
ciliary basal body
centrosom
projekcija ćelije
ciliary tip
citoskelet
Treplja
motile cilium
Biološki proces Ježev signalni put
protein stabilization
intraciliary transport
intraciliary transport involved in cilium assembly
cilium assembly
GO:0022610 biološki proces
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001168618
NM_020153

NM_023831

RefSeq (bjelančevina)

NP_001162089
NP_064538

NP_076320

Lokacija (UCSC)Chr 11: 118.54 – 118.57 MbChr 9: 44.68 – 44.7 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 304 aminokiseline, a molekulska težina34.286 Da.[8].

1020304050
MADNSSDECEEENNKEKKKTSQLTPQRGFSENEDDDDDDDDSSETDSDSD
DDDEEHGAPLEGAYDPADYEHLPVSAEIKELFQYISRYTPQLIDLDHKLK
PFIPDFIPAVGDIDAFLKVPRPDGKPDNLGLLVLDEPSTKQSDPTVLSLW
LTENSKQHNITQHMKVKSLEDAEKNPKAIDTWIESISELHRSKPPATVHY
TRPMPDIDTLMQEWSPEFEELLGKVSLPTAEIDCSLAEYIDMICAILDIP
VYKSRIQSLHLLFSLYSEFKNSQHFKALAEGKKAFTPSSNSTSQAGDMET
LTFS

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000118096 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002031 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ O'Brien KP, Tapia-Paez I, Stahle-Backdahl M, Kedra D, Dumanski JP (Jul 2000). "Characterization of five novel human genes in the 11q13-q22 region". Biochem Biophys Res Commun. 273 (1): 90–4. doi:10.1006/bbrc.2000.2910. PMID 10873569.
  6. ^ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  7. ^ "Entrez Gene: C11orf60 chromosome 11 open reading frame 60".
  8. ^ "UniProt, Q9NQC8". Pristupljeno 23. 8. 2021.

Dopunska literatura

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