HSPC159

Galektinu-srodni protein, znan i kao HSPC159, jest ljudski gen sa hromosoma 2.

HSPC159
Dostupne strukture PDB Pretraga ortologa: PDBe RCSB Spisak PDB ID kodova 2JJ6, 3B9C
Identifikatori
Aliasi	LGALSL
Vanjski ID-jevi	OMIM: 617902 MGI: 1916114 HomoloGene: 8581 GeneCards: LGALSL
Lokacija gena (čovjek) Hrom. Hromosom 2 (čovjek) Bend 2p14 Početak 64,453,969 bp Kraj 64,461,381 bp
Lokacija gena (miš) Hrom. Hromosom 11 (miš) Bend 11 A3.1|11 13.53 cM Početak 20,773,576 bp Kraj 20,781,056 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ortolozi
Vrste	Čovjek	Miš
Entrez	29094	216551
Ensembl	ENSG00000119862	ENSMUSG00000042363
UniProt	Q3ZCW2	Q8VED9
RefSeq (mRNK)	NM_014181	NM_173752
RefSeq (bjelančevina)	NP_054900	NP_776113
Lokacija (UCSC)	Chr 2: 64.45 – 64.46 Mb	Chr 11: 20.77 – 20.78 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Amiokiselininska sekvenca

Dužina polipeptidnog lanca je 172 aminokiseline, a molkekulska iežina 18.986 Da.

• C: Cistein
• D: Asparaginska kiselina
• E: Glutaminska kiselina
• F: Fenilalanin
• G: Glicin
• H: Histidin
• I: Izoleucin
• K: Lizin
• L: Leucin
• M: Metionin
• N: Asparagin
• P: Prolin
• Q: Glutamin
• R: Arginin
• S: Serin
• T: Treonin
• V: Valin
• W: Triptofan
• Y: Tirozin

10		20		30		40		50
MAGSVADSDA		VVKLDDGHLN		NSLSSPVQAD		VYFPRLIVPF		CGHIKGGMRP
GKKVLVMGIV		DLNPESFAIS		LTCGDSEDPP		ADVAIELKAV		FTDRQLLRNS
CISGERGEEQ		SAIPYFPFIP		DQPFRVEILC		EHPRFRVFVD		GHQLFDFYHR
IQTLSAIDTI		KINGDLQITK		LG

Dopunska literatura

• Ahmed H, Vasta GR (2007). "Unlike mammalian GRIFIN, the zebrafish homologue (DrGRIFIN) represents a functional carbohydrate-binding galectin". Biochem. Biophys. Res. Commun. 371 (3): 350–5. doi:10.1016/j.bbrc.2008.04.078. PMC 2766801. PMID 18448074.
• Zhou D, Sun J, Zhao W, et al. (2006). "Expression, purification, crystallization and preliminary X-ray characterization of the GRP carbohydrate-recognition domain from Homo sapiens". Acta Crystallographica Section F. 62 (Pt 5): 474–6. doi:10.1107/S1744309106012875. PMC 2219983. PMID 16682780.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.