GET4

GET4
Identifikatori
Aliasi	GET4
Vanjski ID-jevi	OMIM: 612056 MGI: 1914854 HomoloGene: 41080 GeneCards: GET4
Lokacija gena (čovjek)
Hrom.	Hromosom 7 (čovjek)
Kraj	896,436 bp
Lokacija gena (miš)
Hrom.	Hromosom 5 (miš)
Kraj	139,255,806 bp
Obrazac RNK ekspresije
	Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine; • chaperone binding;
Ćelijska komponenta	• BAT3 complex; • citosol; • citoplazma; • nukleoplazma; • Jedarce;
Biološki proces	• cytoplasmic sequestering of protein; • tail-anchored membrane protein insertion into ER membrane; • maintenance of unfolded protein involved in ERAD pathway; • protein insertion into ER membrane;
	Izvori:Amigo / QuickGO
Ortolozi
	51608
	67604
	ENSG00000239857
	ENSMUSG00000025858
	Q7L5D6
	Q9D1H7
	NM_015949
	NM_001163316; NM_026269; NM_001359238
	NP_057033
	NP_001156788; NP_080545; NP_001346167
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

GET4 je protein koji je kod ljudi kodiran genom GET4.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 327 aminokiselina, а molekulska težina 36.504 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MAAAAAMAEQ	ESARNGGRNR	GGVQRVEGKL	RASVEKGDYY	EAHQMYRTLF
FRYMSQSKHT	EARELMYSGA	LLFFSHGQQN	SAADLSMLVL	ESLEKAEVEV
ADELLENLAK	VFSLMDPNSP	ERVTFVSRAL	KWSSGGSGKL	GHPRLHQLLA
LTLWKEQNYC	ESRYHFLHSA	DGEGCANMLV	EYSTSRGFRS	EVDMFVAQAV
LQFLCLKNKS	SASVVFTTYT	QKHPSIEDGP	PFVEPLLNFI	WFLLLAVDGG
KLTVFTVLCE	QYQPSLRRDP	MYNEYLDRIG	QLFFGVPPKQ	TSSYGGLLGN
LLTSLMGSSE	QEDGEESPSD	GSPIELD

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000239857 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025858 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
^ "Entrez Gene: C7orf20 chromosome 7 open reading frame 20".
^ "UniProt, Q7L5D6" (jezik: англ.). Pristupljeno 23. 9. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura

Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

Vanjski linkovi

Lokacija ljudskog genoma GET4 i stranica sa detaljima o genu GET4 u UCSC Genome Browseru.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000239857 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025858 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10810093-5] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

[entrez-6] "Entrez Gene: C7orf20 chromosome 7 open reading frame 20".

[UniProt-7] "UniProt, Q7L5D6" (jezik: англ.). Pristupljeno 23. 9. 2021.CS1 održavanje: nepoznati jezik (link)

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