FOXB1

FOXB1
Identifikatori
Aliasi	FOXB1
Vanjski ID-jevi	MGI: 1927549 HomoloGene: 8138 GeneCards: FOXB1
Lokacija gena (čovjek)
Hrom.	Hromosom 15 (čovjek)
Kraj	60,061,730 bp
Lokacija gena (miš)
Hrom.	Hromosom 9 (miš)
Kraj	69,668,222 bp
Ontologija gena
Molekularna funkcija	• vezivanje sa DNK; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • GO:0001948, GO:0016582 vezivanje za proteine; • sequence-specific DNA binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• jedro;
Biološki proces	• visual learning; • somitogenesis; • GO:1904089 negative regulation of neuron apoptotic process; • mammillary body development; • mammillothalamic axonal tract development; • GO:0009373 regulation of transcription, DNA-templated; • axon target recognition; • mammary gland lobule development; • thalamus development; • transcription, DNA-templated; • floor plate development; • telencephalon cell migration; • cell migration in diencephalon; • inferior colliculus development; • spinal cord development; • urogenital system development; • lactation; • midbrain development; • epithelial cell differentiation involved in mammary gland alveolus development; • hypothalamus cell migration; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II; • anatomical structure morphogenesis; • Ćelijska diferencijacija;
	Izvori:Amigo / QuickGO
Ortolozi
	27023
	64290
	ENSG00000171956
	ENSMUSG00000059246
	Q99853
	Q64732
	NM_012182
	NM_022378
	NP_036314
	NP_071773
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Viljuškasta kutija B1 ja protein koji je kod ljudi kodiran genom FOXB1.^[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 325 aminokiselina, a molekulska težina 34.978 Da.^[6].

10	20	30	40	50
MPRPGRNTYS	DQKPPYSYIS	LTAMAIQSSP	EKMLPLSEIY	KFIMDRFPYY
RENTQRWQNS	LRHNLSFNDC	FIKIPRRPDQ	PGKGSFWALH	PSCGDMFENG
SFLRRRKRFK	VLKSDHLAPS	KPADAAQYLQ	QQAKLRLSAL	AASGTHLPQM
PAAAYNLGGV	AQPSGFKHPF	AIENIIAREY	KMPGGLAFSA	MQPVPAAYPL
PNQLTTMGSS	LGTGWPHVYG	SAGMIDSATP	ISMASGDYSA	YGVPLKPLCH
AAGQTLPAIP	VPIKPTPAAV	PALPALPAPI	PTLLSNSPPS	LSPTSSQTAT
SQSSPATPSE	TLTSPASALH	SVAVH

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171956 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000059246 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Forkhead box B1". Pristupljeno 11. 9. 2014.
^ "UniProt, Q99853". Pristupljeno 14. 7. 2021.

Vanjski linkovi

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171956 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000059246 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Forkhead box B1". Pristupljeno 11. 9. 2014.

[UniProt-6] "UniProt, Q99853". Pristupljeno 14. 7. 2021.

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