ARPP-19
cAMP-regulirani fosfoprotein 19 je protein koji je kod ljudi kodiran genom ARPP19.[5][6][7]
Aminokiselinska sekvenca
urediDužina polipeptidnog lanca je 112 aminokiselina, a molekulska težina 12.323 Da.[8].
- Simboli
C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin
10 | 20 | 30 | 40 | 50 | ||||
---|---|---|---|---|---|---|---|---|
MSAEVPEAAS | AEEQKEMEDK | VTSPEKAEEA | KLKARYPHLG | QKPGGSDFLR | ||||
KRLQKGQKYF | DSGDYNMAKA | KMKNKQLPTA | APDKTEVTGD | HIPTPQDLPQ | ||||
RKPSLVASKL | AG |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000128989 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000007656 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Dulubova I, Horiuchi A, Snyder GL, Girault JA, Czernik AJ, Shao L, Ramabhadran R, Greengard P, Nairn AC (2001). "ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins". J. Neurochem. 77 (1): 229–38. doi:10.1046/j.1471-4159.2001.t01-1-00191.x. PMID 11279279.
- ^ Peyrollier K, Héron L, Virsolvy-Vergine A, Le Cam A, Bataille D (1996). "Alpha endosulfine is a novel molecule, structurally related to a family of phosphoproteins". Biochem. Biophys. Res. Commun. 223 (3): 583–6. doi:10.1006/bbrc.1996.0938. PMID 8687439.
- ^ "Entrez Gene: ARPP-19 cyclic AMP phosphoprotein, 19 kD".
- ^ "UniProt, P56211". Pristupljeno 12. 7. 2021.
Dopunska literatura
uredi- Kim SH, Nairn AC, Cairns N, Lubec G (2001). "Decreased levels of ARPP-19 and PKA in brains of Down syndrome and Alzheimer's disease". J. Neural Transm. Suppl. (61): 263–72. doi:10.1007/978-3-7091-6262-0_21. PMID 11771749.
- Chin LS, Singh SK, Wang Q, Murray SF (2000). "Identification of okadaic-acid-induced genes by mRNA differential display in glioma cells". J. Biomed. Sci. 7 (2): 152–9. doi:10.1007/BF02256622. PMID 10754390.
- Heron L, Virsolvy A, Peyrollier K, Gribble FM, Le Cam A, Ashcroft FM, Bataille D (1998). "Human alpha-endosulfine, a possible regulator of sulfonylurea-sensitive KATP channel: molecular cloning, expression and biological properties". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8387–91. doi:10.1073/pnas.95.14.8387. PMC 20985. PMID 9653196.
- Brené S, Lindefors N, Ehrlich M, Taubes T, Horiuchi A, Kopp J, Hall H, Sedvall G, Greengard P, Persson H (1994). "Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue". J. Neurosci. 14 (3 Pt 1): 985–98. doi:10.1523/JNEUROSCI.14-03-00985.1994. PMC 6577526. PMID 8120638.
- Horiuchi A, Williams KR, Kurihara T, Nairn AC, Greengard P (1990). "Purification and cDNA cloning of ARPP-16, a cAMP-regulated phosphoprotein enriched in basal ganglia, and of a related phosphoprotein, ARPP-19". J. Biol. Chem. 265 (16): 9476–84. PMID 2160982.
Vanjski linkovi
uredi- Lokacija ljudskog genoma ARPP19 i stranica sa detaljima o genu ARPP19 u UCSC Genome Browseru.