cAMP-regulirani fosfoprotein 19 je protein koji je kod ljudi kodiran genom ARPP19.[5][6][7]

ARPP-19
Identifikatori
AliasiARPP19
Vanjski ID-jeviOMIM: 605487 MGI: 1891691 HomoloGene: 21318 GeneCards: ARPP19
Lokacija gena (čovjek)
Hromosom 15 (čovjek)
Hrom.Hromosom 15 (čovjek)[1]
Hromosom 15 (čovjek)
Genomska lokacija za ARPP-19
Genomska lokacija za ARPP-19
Bend15q21.2Početak52,547,045 bp[1]
Kraj52,569,883 bp[1]
Lokacija gena (miš)
Hromosom 9 (miš)
Hrom.Hromosom 9 (miš)[2]
Hromosom 9 (miš)
Genomska lokacija za ARPP-19
Genomska lokacija za ARPP-19
Bend9|9 DPočetak75,037,614 bp[2]
Kraj75,060,313 bp[2]
Obrazac RNK ekspresije




Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija protein phosphatase 2A binding
potassium channel regulator activity
signaling receptor binding
phosphatase inhibitor activity
protein phosphatase inhibitor activity
protein phosphatase regulator activity
Ćelijska komponenta nukleoplazma
citoplazma
Biološki proces Ćelijska dioba
positive regulation of glucose import
ćelijski ciklus
positive regulation of gluconeogenesis
G2/M transition of mitotic cell cycle
GO:0048553 negative regulation of catalytic activity
negative regulation of protein dephosphorylation
GO:0007067 Mitoza
negative regulation of phosphoprotein phosphatase activity
regulation of phosphoprotein phosphatase activity
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001306191
NM_001306195
NM_001306196
NM_006628
NM_001330309

NM_001142655
NM_021548

RefSeq (bjelančevina)

NP_001293120
NP_001293124
NP_001293125
NP_001317238
NP_006619

NP_001136127
NP_067523
NP_001344807
NP_001344808
NP_001344809

NP_001344810

Lokacija (UCSC)Chr 15: 52.55 – 52.57 MbChr 9: 75.04 – 75.06 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 112 aminokiselina, a molekulska težina 12.323 Da.[8].

Simboli
1020304050
MSAEVPEAASAEEQKEMEDKVTSPEKAEEAKLKARYPHLGQKPGGSDFLR
KRLQKGQKYFDSGDYNMAKAKMKNKQLPTAAPDKTEVTGDHIPTPQDLPQ
RKPSLVASKLAG

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128989 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000007656 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Dulubova I, Horiuchi A, Snyder GL, Girault JA, Czernik AJ, Shao L, Ramabhadran R, Greengard P, Nairn AC (2001). "ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins". J. Neurochem. 77 (1): 229–38. doi:10.1046/j.1471-4159.2001.t01-1-00191.x. PMID 11279279.
  6. ^ Peyrollier K, Héron L, Virsolvy-Vergine A, Le Cam A, Bataille D (1996). "Alpha endosulfine is a novel molecule, structurally related to a family of phosphoproteins". Biochem. Biophys. Res. Commun. 223 (3): 583–6. doi:10.1006/bbrc.1996.0938. PMID 8687439.
  7. ^ "Entrez Gene: ARPP-19 cyclic AMP phosphoprotein, 19 kD".
  8. ^ "UniProt, P56211". Pristupljeno 12. 7. 2021.

Dopunska literatura

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Vanjski linkovi

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