Akirin-2 jest protein koji je kod ljudi kodiran genom AKIRIN2.[5]

AKIRIN2
Identifikatori
AliasiAKIRIN2
Vanjski ID-jeviOMIM: 615165 MGI: 1889364 HomoloGene: 9988 GeneCards: AKIRIN2
Lokacija gena (čovjek)
Hromosom 6 (čovjek)
Hrom.Hromosom 6 (čovjek)[1]
Hromosom 6 (čovjek)
Genomska lokacija za AKIRIN2
Genomska lokacija za AKIRIN2
Bend6q15Početak87,674,860 bp[1]
Kraj87,702,233 bp[1]
Lokacija gena (miš)
Hromosom 4 (miš)
Hrom.Hromosom 4 (miš)[2]
Hromosom 4 (miš)
Genomska lokacija za AKIRIN2
Genomska lokacija za AKIRIN2
Bend4|4 A5Početak34,550,937 bp[2]
Kraj34,566,908 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija vezivanje enzima
GO:0001948, GO:0016582 vezivanje za proteine
Ćelijska komponenta transcription repressor complex
jedro
nukleoplazma
Biološki proces multicellular organism development
positive regulation of endopeptidase activity
response to lipopolysaccharide
Urođeni imunski sistem
GO:0045996 negative regulation of transcription, DNA-templated
GO:0009373 regulation of transcription, DNA-templated
GO:1901227 negative regulation of transcription by RNA polymerase II
negative regulation of gene expression
transcription, DNA-templated
positive regulation of cell population proliferation
positive regulation of interleukin-6 production
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
immune system process
embryo development ending in birth or egg hatching
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_018064

NM_001007589
NM_026019

RefSeq (bjelančevina)

NP_060534

NP_001007590

Lokacija (UCSC)Chr 6: 87.67 – 87.7 MbChr 4: 34.55 – 34.57 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 203 aminokiseline, а molekulska težina 22.496 Da.[6]

1020304050
MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPTSAAASPLSAAAATAAS
FSAAAASPQKYLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLET
SFQQTDPCCTSDAQPHAFLLSGPASPGTSSAASSPLKKEQPLFTLRQVGM
ICERLLKEREEKVREEYEEILNTKLAEQYDAFVKFTHDQIMRRYGEQPAS
YVS

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135334 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028291 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: C6orf166 chromosome 6 open reading frame 166".
  6. ^ "UniProt, Q53H80" (jezik: engleski). Pristupljeno 6. 10. 2021.

Dopunska literatura

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Vanjski linkovi

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