Androgeno ovisni TFPI-regulirajući protein jest protein koji je kod ljudi kodiran genom ADTRP.[5]

ADTRP
Identifikatori
AliasiADTRP
Vanjski ID-jeviOMIM: 614348 MGI: 1924596 HomoloGene: 13107 GeneCards: ADTRP
Lokacija gena (čovjek)
Hromosom 6 (čovjek)
Hrom.Hromosom 6 (čovjek)[1]
Hromosom 6 (čovjek)
Genomska lokacija za ADTRP
Genomska lokacija za ADTRP
Bend6p24.1Početak11,712,054 bp[1]
Kraj11,807,046 bp[1]
Lokacija gena (miš)
Hromosom 13 (miš)
Hrom.Hromosom 13 (miš)[2]
Hromosom 13 (miš)
Genomska lokacija za ADTRP
Genomska lokacija za ADTRP
Bend13|13 A4Početak41,916,624 bp[2]
Kraj42,001,160 bp[2]
Ontologija gena
Molekularna funkcija hydrolase activity
Ćelijska komponenta integral component of membrane
ćelijska membrana
Endomembranski sistem
Kaveole
cell surface
membrana
intracellular anatomical structure
Biološki proces GO:1901313 positive regulation of gene expression
negative regulation of blood coagulation
long-chain fatty acid catabolic process
cellular response to steroid hormone stimulus
positive regulation of protein phosphorylation
cell migration involved in sprouting angiogenesis
negative regulation of leukocyte migration
negative regulation of extracellular matrix constituent secretion
protein kinase B signaling
negative regulation of protein secretion
cellular response to oxidised low-density lipoprotein particle stimulus
negative regulation of leukocyte cell-cell adhesion
negative regulation of lymphocyte migration
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001143948
NM_032744

NM_001145875
NM_175417

RefSeq (bjelančevina)

NP_001137420
NP_116133

NP_001139347
NP_780626

Lokacija (UCSC)Chr 6: 11.71 – 11.81 MbChr 13: 41.92 – 42 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca uredi

Dužina polipeptidnog lanca je 230 aminokiselina, а molekulska težina 26.842 Da.[6]

1020304050
MTKTSTCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLN
LLLQTIFYGVTCLDDVLKRTKGGKDIKFLTAFRDLLFTTLAFPVSTFVFL
AFWILFLYNRDLIYPKVLDTVIPVWLNHAMHTFIFPITLAEVVLRPHSYP
SKKTGLTLLAAASIAYISRILWLYFETGTWVYPVFAKLSLLGLAAFFSLS
YVFIASIYLLGEKLNHWKWGDMRQPRKKRK

Reference uredi

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000111863 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058022 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Androgen-dependent TFPI-regulating protein". Pristupljeno 7. 2. 2013.
  6. ^ "UniProt, Q96IZ2" (jezik: engleski). Pristupljeno 30. 9. 2021.