ACRV1

ACRV1
Identifikatori
Aliasi	ACRV1
Vanjski ID-jevi	OMIM: 102525 MGI: 104590 HomoloGene: 1219 GeneCards: ACRV1
Lokacija gena (čovjek)
Hrom.	Hromosom 11 (čovjek)
Kraj	125,680,874 bp
Lokacija gena (miš)
Hrom.	Hromosom 9 (miš)
Kraj	36,610,139 bp
Obrazac RNK ekspresije
	; ; ; ;
	Više referentnih podataka o ekspresiji
Ortolozi
	56
	11451
	ENSG00000134940
	ENSMUSG00000032110
	P26436
	P50289
NM_020115; NM_001612; NM_020069; NM_020107; NM_020108;
	NM_020109; NM_020110; NM_020111; NM_020112; NM_020113; NM_020114
	NM_007391
	NP_001603; NP_064454; NP_064492; NP_064493
	NP_031417
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Interaktivni kinazni protein 1 (PRKA) je protein koji je kod ljudi kodiran genom AKIP1.^[5]

Ovaj gen kodira jedarni protein koji stupa u interakciju s katalitskom podjedinicom protein-kinaze A i regulira učinak signalnog puta protein-kinaze, ovisnog o cAMP-u na kaskadu aktivacije NF-kapa-B. Za ovaj gen opisane su i alternativno prerađene varijante transkripta (prema RefSeq, OKt 2011].

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 210 aminokiselina, a molekulska težina 23.114 Da.^[6]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MDNCLAAAAL	NGVDRRSLQR	SARLALEVLE	RAKRRAVDWH	ALERPKGCMG
VLAREAPHLE	KQPAAGPQRV	LPGEREERPP	TLSASFRTMA	EFMDYTSSQC
GKYYSSVPEE	GGATHVYRYH	RGESKLHMCL	DIGNGQRKDR	KKTSLGPGGS
YQISEHAPEA	SQPAENISKD	LYIEVYPGTY	SVTVGSNDLT	KKTHVVAVDS
GQSVDLVFPV

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000134940 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032110 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: A kinase (PRKA) interacting protein 1".
^ "UniProt, Q9NQ31". Pristupljeno 15. 8. 2021.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000134940 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032110 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: A kinase (PRKA) interacting protein 1".

[UniProt-6] "UniProt, Q9NQ31". Pristupljeno 15. 8. 2021.

[5]

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