AAGAB

Alfa- i gama-adaptin vezani protein, znan i kao AAGAB, je ljudski gen.

AAGAB
Identifikatori
Aliasi	AAGAB
Vanjski ID-jevi	OMIM: 614888 MGI: 1914189 HomoloGene: 11648 GeneCards: AAGAB
Lokacija gena (čovjek) Hrom. Hromosom 15 (čovjek) Bend 15q23 Početak 67,200,667 bp Kraj 67,255,195 bp
Lokacija gena (miš) Hrom. Hromosom 9 (miš) Bend 9|9 C Početak 63,509,942 bp Kraj 63,551,870 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • citoplazma • citosol • nuclear speck Biološki proces • protein transport Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	79719	66939
Ensembl	ENSG00000103591	ENSMUSG00000037257
UniProt	Q6PD74	Q8R2R3
RefSeq (mRNK)	NM_001271885 NM_001271886 NM_024666	NM_025857 NM_001357323
RefSeq (bjelančevina)	NP_001258814 NP_001258815 NP_078942	NP_080133 NP_001344252
Lokacija (UCSC)	Chr 15: 67.2 – 67.26 Mb	Chr 9: 63.51 – 63.55 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 315 aminokiselina, a molekulska težina 34 594 Da..

10		20		30		40		50
MAAGVPCALV		TSCSSVFSGD		QLVQHILGTE		DLIVEVTSND		AVRFYPWTID
NKYYSADINL		CVVPNKFLVT		AEIAESVQAF		VVYFDSTQKS		GLDSVSSWLP
LAKAWLPEVM		ILVCDRVSED		GINRQKAQEW		CIKHGFELVE		LSPEELPEED
DDFPESTGVK		RIVQALNANV		WSNVVMKNDR		NQGFSLLNSL		TGTNHSIGSA
DPCHPEQPHL		PAADSTESLS		DHRGGASNTT		DAQVDSIVDP		MLDLDIQELA
SLTTGGGDVE		NFERLFSKLK		EMKDKAATLP		HEQRKVHAEK		VAKAFWMAIG
GDRDEIEGLS		SDEEH

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

Dopunska literatura

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.