ZCCHC2
Protein koji sadrži CCHC-domen cinkovog prsta 2 je protein koji je kod ljudi kodiran genom ZCCHC2.[5][6]
| ZCCHC2 | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||||||||||||||||
| Aliasi | ZCCHC2 | ||||||||||||||||||||||||
| Vanjski ID-jevi | MGI: 2444114 HomoloGene: 9808 GeneCards: ZCCHC2 | ||||||||||||||||||||||||
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| Ortolozi | |||||||||||||||||||||||||
| Vrste | Čovjek | Miš | |||||||||||||||||||||||
| Entrez | |||||||||||||||||||||||||
| Ensembl | |||||||||||||||||||||||||
| UniProt | |||||||||||||||||||||||||
| RefSeq (mRNK) | |||||||||||||||||||||||||
| RefSeq (bjelančevina) | |||||||||||||||||||||||||
| Lokacija (UCSC) | Chr 18: 62.52 – 62.59 Mb | Chr 1: 105.92 – 105.96 Mb | |||||||||||||||||||||||
| PubMed pretraga | [3] | [4] | |||||||||||||||||||||||
| Wikipodaci | |||||||||||||||||||||||||
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Dužina polipeptidnog lanca je 1.178 aminokiselina, sa molekulskom težinom od 125 936[7].
Aminokiselinska sekvenca
- Simboli
C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MLRMKLPLKP | THPAEPPPEA | EEPEADARPG | AKAPSRRRRD | CRPPPPPPPP | ||||
| AGPSRGPLPP | PPPPRGLGPP | VAGGAAAGAG | MPGGGGGPSA | ALREQERVYE | ||||
| WFGLVLGSAQ | RLEFMCGLLD | LCNPLELRFL | GSCLEDLARK | DYHYLRDSEA | ||||
| KANGLSDPGP | LADFREPAVR | SRLIVYLALL | GSENREAAGR | LHRLLPQVDS | ||||
| VLKSLRAARG | EGSRGGAEDE | RGEDGDGEQD | AEKDGSGPEG | GIVEPRVGGG | ||||
| LGSRAQEELL | LLFTMASLHP | AFSFHQRVTL | REHLERLRAA | LRGGPEDAEV | ||||
| EVEPCKFAGP | RAQNNSAHGD | YMQNNESSLI | EQAPIPQDGL | TVAPHRAQRE | ||||
| AVHIEKIMLK | GVQRKRADKY | WEYTFKVNWS | DLSVTTVTKT | HQELQEFLLK | ||||
| LPKELSSETF | DKTILRALNQ | GSLKREERRH | PDLEPILRQL | FSSSSQAFLQ | ||||
| SQKVHSFFQS | ISSDSLHSIN | NLQSSLKTSK | ILEHLKEDSS | EASSQEEDVL | ||||
| QHAIIHKKHT | GKSPIVNNIG | TSCSPLDGLT | MQYSEQNGIV | DWRKQSCTTI | ||||
| QHPEHCVTSA | DQHSAEKRSL | SSINKKKGKP | QTEKEKIKKT | DNRLNSRING | ||||
| IRLSTPQHAH | GGTVKDVNLD | IGSGHDTCGE | TSSESYSSPS | SPRHDGRESF | ||||
| ESEEEKDRDT | DSNSEDSGNP | STTRFTGYGS | VNQTVTVKPP | VQIASLGNEN | ||||
| GNLLEDPLNS | PKYQHISFMP | TLHCVMHNGA | QKSEVVVPAP | KPADGKTIGM | ||||
| LVPSPVAISA | IRESANSTPV | GILGPTACTG | ESEKHLELLA | SPLPIPSTFL | ||||
| PHSSTPALHL | TVQRLKLPPP | QGSSESCTVN | IPQQPPGSLS | IASPNTAFIP | ||||
| IHNPGSFPGS | PVATTDPITK | SASQVVGLNQ | MVPQIEGNTG | TVPQPTNVKV | ||||
| VLPAAGLSAA | QPPASYPLPG | SPLAAGVLPS | QNSSVLSTAA | TSPQPASAGI | ||||
| SQAQATVPPA | VPTHTPGPAP | SPSPALTHST | AQSDSTSYIS | AVGNTNANGT | ||||
| VVPPQQMGSG | PCGSCGRRCS | CGTNGNLQLN | SYYYPNPMPG | PMYRVPSFFT | ||||
| LPSICNGSYL | NQAHQSNGNQ | LPFFLPQTPY | ANGLVHDPVM | GSQANYGMQQ | ||||
| MAGFGRFYPV | YPAPNVVANT | SGSGPKKNGN | VSCYNCGVSG | HYAQDCKQSS | ||||
| MEANQQGTYR | LRYAPPLPPS | NDTLDSAD |
Reference
uredi- ^ a b c GRCh38: Ensembl release 89: ENSG00000141664 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038866 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
- ^ "Entrez Gene: ZCCHC2 zinc finger, CCHC domain containing 2".
- ^ "UniProt, Q9C0B9". Pristupljeno 12. 9. 2017.
Dopunska literatura
uredi- Dias Neto E; Correa RG; Verjovski-Almeida S; et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.
- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Wiemann S; Weil B; Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Simpson JC; Wellenreuther R; Poustka A; et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Clark HF; Gurney AL; Abaya E; et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Ota T; Suzuki Y; Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Wiemann S; Arlt D; Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Mehrle A; Rosenfelder H; Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Olsen JV; Blagoev B; Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.