Dodatni češljoliki protein 3 (Drosophila ) jest protein koji je kod ljudi kodiran genom ASXL3 .[ 5]
Dužina polipeptidnog lanca iznosi 2.248 aminokiselina , a molekulska masa – 241.919.
Aminokiselinska sekvenca
Simboli
10 20 30 40 50
MKDKRKKKDR TWAEAARLAL EKHPNSPMTA KQILEVIQKE GLKETSGTSP
LACLNAMLHT NTRIGDGTFF KIPGKSGLYA LKKEESSCPA DGTLDLVCES
ELDGTDMAEA NAHGEENGVC SKQVTDEASS TRDSSLTNTA VQSKLVSSFQ
QHTKKALKQA LRQQQKRRNG VSMMVNKTVP RVVLTPLKVS DEQSDSPSGS
ESKNGEADSS DKEMKHGQKS PTGKQTSQHL KRLKKSGLGH LKWTKAEDID
IETPGSILVN TNLRALINKH TFASLPQHFQ QYLLLLLPEV DRQMGSDGIL
RLSTSALNNE FFAYAAQGWK QRLAEGEFTP EMQLRIRQEI EKEKKTEPWK
EKFFERFYGE KLGMSREESV KLTTGPNNAG AQSSSSCGTS GLPVSAQTAL
AEQQPKSMKS PASPEPGFCA TLCPMVEIPP KDIMAELESE DILIPEESVI
QEEIAEEVET SICECQDENH KTIPEFSEEA ESLTNSHEEP QIAPPEDNLE
SCVMMNDVLE TLPHIEVKIE GKSESPQEEM TVVIDQLEVC DSLIPSTSSM
THVSDTEHKE SETAVETSTP KIKTGSSSLE GQFPNEGIAI DMELQSDPEE
QLSENACISE TSFSSESPEG ACTSLPSPGG ETQSTSEESC TPASLETTFC
SEVSSTENTD KYNQRNSTDE NFHASLMSEI SPISTSPEIS EASLMSNLPL
TSEASPVSNL PLTSETSPMS DLPLTSETSS VSSMLLTSET TFVSSLPLPS
ETSPISNSSI NERMAHQQRK SPSVSEEPLS PQKDESSATA KPLGENLTSQ
QKNLSNTPEP IIMSSSSIAP EAFPSEDLHN KTLSQQTCKS HVDTEKPYPA
SIPELASTEM IKVKNHSVLQ RTEKKVLPSP LELSVFSEGT DNKGNELPSA
KLQDKQYISS VDKAPFSEGS RNKTHKQGST QSRLETSHTS KSSEPSKSPD
GIRNESRDSE ISKRKTAEQH SFGICKEKRA RIEDDQSTRN ISSSSPPEKE
QPPREEPRVP PLKIQLSKIG PPFIIKSQPV SKPESRASTS TSVSGGRNTG
ARTLADIKAR AQQARAQREA AAAAAVAAAA SIVSGAMGSP GEGGKTRTLA
HIKEQTKAKL FAKHQARAHL FQTSKETRLP PPLSSKEGPP NLEVSSTPET
KMEGSTGVII VNPNCRSPSN KSAHLRETTT VLQQSLNPSK LPETATDLSV
HSSDENIPVS HLSEKIVSST SSENSSVPML FNKNSVPVSV CSTAISGAIK
EHPFVSSVDK SSVLMSVDSA NTTISACNIS MLKTIQGTDT PCIAIIPKCI
ESTPISATTE GSSISSSMDD KQLLISSSSA SNLVSTQYTS VPTPSIGNNL
PNLSTSSVLI PPMGINNRFP SEKIAIPGSE EQATVSMGTT VRAALSCSDS
VAVTDSLVAH PTVAMFTGNM LTINSYDSPP KLSAESLDKN SGPRNRADNS
GKPQQPPGGF APAAINRSIP CKVIVDHSTT LTSSLSLTVS VESSEASLDL
QGRPVRTEAS VQPVACPQVS VISRPEPVAN EGIDHSSTFI AASAAKQDSK
TLPATCTSLR ELPLVPDKLN EPTAPSHNFA EQARGPAPFK SEADTTCSNQ
YNPSNRICWN DDGMRSTGQP LVTHSGSSKQ KEYLEQSCPK AIKTEHANYL
NVSELHPRNL VTNVALPVKS ELHEADKGFR MDTEDFPGPE LPPPAAEGAS
SVQQTQNMKA STSSPMEEAI SLATDALKRV PGAGSSGCRL SSVEANNPLV
TQLLQGNLPL EKVLPQPRLG AKLEINRLPL PLQTTSVGKT APERNVEIPP
SSPNPDGKGY LAGTLAPLQM RKRENHPKKR VARTVGEHTQ VKCEPGKLLV
EPDVKGVPCV ISSGISQLGH SQPFKQEWLN KHSMQNRIVH SPEVKQQKRL
LPSCSFQQNL FHVDKNGGFH TDAGTSHRQQ FYQMPVAARG PIPTAALLQA
SSKTPVGCNA FAFNRHLEQK GLGEVSLSSA PHQLRLANML SPNMPMKEGD
EVGGTAHTMP NKALVHPPPP PPPPPPPPLA LPPPPPPPPP LPPPLPNAEV
PSDQKQPPVT METTKRLSWP QSTGICSNIK SEPLSFEEGL SSSCELGMKQ
VSYDQNEMKE QLKAFALKSA DFSSYLLSEP QKPFTQLAAQ KMQVQQQQQL
CGNYPTIHFG STSFKRAASA IEKSIGILGS GSNPATGLSG QNAQMPVQNF
ADSSNADELE LKCSCRLKAM IVCKGCGAFC HDDCIGPSKL CVACLVVR
Dopunska literatura
uredi
Fisher CL, Randazzo F, Humphries RK, Brock HW (mart 2006). "Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family". Gene . 369 : 109–18. doi :10.1016/j.gene.2005.10.033 . PMID 16412590 .
Katoh M, Katoh M (juni 2004). "Identification and characterization of ASXL3 gene in silico". International Journal of Oncology . 24 (6): 1617–22. PMID 15138607 .