Ubikvitinska karboksil-terminalna hidrolaza 51 je enzim koji je kod ljudi kodiran genom USP51.[5][6]

USP51
Identifikatori
AliasiUSP51
Vanjski ID-jeviMGI: 3588217 HomoloGene: 71495 GeneCards: USP51
Lokacija gena (čovjek)
Hromosom X
Hrom.Hromosom X[1]
Hromosom X
Genomska lokacija za USP51
Genomska lokacija za USP51
BendXp11.21Početak55,484,616 bp[1]
Kraj55,489,848 bp[1]
Lokacija gena (miš)
Hromosom X (miš)
Hrom.Hromosom X (miš)[2]
Hromosom X (miš)
Genomska lokacija za USP51
Genomska lokacija za USP51
BendX|X F3Početak151,789,465 bp[2]
Kraj151,792,412 bp[2]
Ontologija gena
Molekularna funkcija thiol-dependent deubiquitinase
vezivanje iona cinka
GO:0070122 peptidase activity
cysteine-type peptidase activity
hydrolase activity
vezivanje iona metala
chromatin binding
GO:0031493 histone binding
Ćelijska komponenta hromosom
Biološki proces protein deubiquitination
ubiquitin-dependent protein catabolic process
Proteoliza
histone deubiquitination
regulation of response to DNA damage stimulus
regulation of cell cycle process
regulation of double-strand break repair via homologous recombination
regulation of double-strand break repair via nonhomologous end joining
GO:0100026 Popravka DNK
cellular response to DNA damage stimulus
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_201286

NM_001137547

RefSeq (bjelančevina)

NP_958443

NP_001131019

Lokacija (UCSC)Chr X: 55.48 – 55.49 MbChr X: 151.79 – 151.79 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000247746 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067215 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
  6. ^ "Entrez Gene: USP51 ubiquitin specific peptidase 51".

Dopunska literatura

uredi