N-acetilglukozaminiltransferaza
Alfa-1,6-manozil-glikoprotein 4-beta-N-acetilglukozaminiltransferaza (EC2.4.1.201, N-acetilglukozaminiltransferaza VI, N-glikozil-oligosaharid-glikoprotein N-acetilglukozaminiltransferaza VI, uridin difosfoacetilglukozamin-glikopeptid beta-1->4-acetilglukozaminil, protalikozaminil-glukozaminil 1,4-N-acetilglukozaminiltransferaza, GnTVI) je enzim sa sistematskim nazivom UDP-N-acetil-D-glukozamin:2,6- bis(N-acetil-beta-D-glukozaminil)-alfa-D-manozil-glikoprotein 4-beta-N-acetil-D-glukozaminiltransferaza.[1][2] Ovaj enzim katalizira sljedeću hemijsku reakciju
| Alfa-1,6-manozil-glikoprotein 4-beta-N-acetilglukozaminiltransferaza | |
|---|---|
| Identifikatori | |
| Simbol | ? |
| CAS broj | |
- UDP-N-acetil-D-glukozamin + 2,6-bis(N-acetil-beta-D-glukozaminil)-alfa-D-manozil-R UDP + 2,4,6-tris(N-acetil-beta-D-glukosaminil)-alfa-D-mannozil-R
R predstavlja ostatak N-vezanog oligosaharida u glikoproteinskom akceptoru.
Reference
uredi- ^ Brockhausen I, Hull E, Hindsgaul O, Schachter H, Shah RN, Michnick SW, Carver JP (juli 1989). "Control of glycoprotein synthesis. Detection and characterization of a novel branching enzyme from hen oviduct, UDP-N-acetylglucosamine:GlcNAc beta 1-6 (GlcNAc beta 1-2)Man alpha-R (GlcNAc to Man) beta-4-N-acetylglucosaminyltransferase VI". The Journal of Biological Chemistry. 264 (19): 11211–21. PMID 2525556.
- ^ Taguchi T, Ogawa T, Inoue S, Inoue Y, Sakamoto Y, Korekane H, Taniguchi N (oktobar 2000). "Purification and characterization of UDP-GlcNAc: GlcNAcbeta 1-6(GlcNAcbeta 1-2)Manalpha 1-R [GlcNAc to Man]-beta 1, 4-N-acetylglucosaminyltransferase VI from hen oviduct". The Journal of Biological Chemistry. 275 (42): 32598–602. doi:10.1074/jbc.m004673200. PMID 10903319.
Vanjski linkovi
uredi- Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase na US National Library of Medicine Medical Subject Headings (MeSH)
