Šablon:UEFA Evropska liga 2017/18 - 1/8
Prve utakmice su igrane 8. marta a uzvratne 15. marta 2018.
| Tim 1 | Rez. | Tim 2 | Prva utakmica | Druga utakmica |
|---|---|---|---|---|
Lazio 
|
4–2 |  Dinamo Kijev
|
2–2 | 2–0 |
RB Leipzig 
|
3–2 |  Zenit Sankt Peterburg
|
2–1 | 1–1 |
Atlético Madrid 
|
8–1 | Lokomotiv Moskva
|
3–0 | 5–1 |
| CSKA Moskva
|
3–3 (a) |  Lyon
|
0–1 | 3–2 |
| Marseille
|
5–2 | Athletic Bilbao
|
3–1 | 2–1 |
Sporting Lisabon 
|
3–2 |  Viktoria Plzeň
|
2–0 | 1–2 (a.e.t.) |
| Borussia Dortmund
|
1–2 |  Red Bull Salzburg
|
1–2 | 0–0 |
| Milan
|
1–5 |  Arsenal
|
0–2 | 1–3 |