THOC2

(Preusmjereno sa MRX35)

Podjedinica THO-kompleksa jest protein koji je kod ljudi kodiran genom THOC2.[5][6]

THOC2
Identifikatori
AliasiTHOC2
Vanjski ID-jeviOMIM: 300395 MGI: 2442413 HomoloGene: 69669 GeneCards: THOC2
Lokacija gena (čovjek)
Hromosom X
Hrom.Hromosom X[1]
Hromosom X
Genomska lokacija za THOC2
Genomska lokacija za THOC2
BendXq25Početak123,600,561 bp[1]
Kraj123,733,056 bp[1]
Lokacija gena (miš)
Hromosom X (miš)
Hrom.Hromosom X (miš)[2]
Hromosom X (miš)
Genomska lokacija za THOC2
Genomska lokacija za THOC2
BendX|X A4Početak40,883,868 bp[2]
Kraj41,009,551 bp[2]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
vezivanje sa RNK
mRNA binding
Ćelijska komponenta THO complex
nuclear speck
THO complex part of transcription export complex
transcription export complex
jedro
nukleoplazma
Biološki proces poly(A)+ mRNA export from nucleus
mRNA processing
mRNA transport
neuron development
viral mRNA export from host cell nucleus
Prerada RNK
generation of neurons
RNA export from nucleus
mRNA export from nucleus
mRNA 3'-end processing
GO:0000767 cell morphogenesis
blastocyst development
Regulacija ekspresije gena
regulation of mRNA export from nucleus
negative regulation of neuron projection development
stem cell division
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001081550
NM_020449

NM_001033422

RefSeq (bjelančevina)

NP_001075019

NP_001028594

Lokacija (UCSC)Chr X: 123.6 – 123.73 MbChr X: 40.88 – 41.01 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

THO2 je dio kompleksa TREX (transkripcija /eksport), koji uključuje TEX1 (MIM 606929), HPR1 (MIM 606930), ALY (MIM 604171) i UAP56 (MIM 606390) (prema OMIM-u).[6]

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125676 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037475 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strasser K, Masuda S, Mason P, Pfannstiel J, Oppizzi M, Rodriguez-Navarro S, Rondon AG, Aguilera A, Struhl K, Reed R, Hurt E (maj 2002). "TREX is a conserved complex coupling transcription with messenger RNA export". Nature. 417 (6886): 304–8. doi:10.1038/nature746. PMID 11979277.
  6. ^ a b "Entrez Gene: THOC2 THO complex 2".

Dopunska literatura

uredi