BEX1

Protein BEX1, znan i kao moždano-eksprimirani X-vezani protein 1 je protein koji je kod čovjeka kodiran genom BEX1.

BEX1
Identifikatori
Aliasi	BEX1
Vanjski ID-jevi	OMIM: 300690 MGI: 1338017 HomoloGene: 135613 GeneCards: BEX1
Lokacija gena (čovjek) Hrom. Hromosom X Bend Xq22.1|Xq22 Početak 103,062,651 bp Kraj 103,064,171 bp
Lokacija gena (miš) Hrom. Hromosom X (miš) Bend X F1|X 57.37 cM Početak 134,967,313 bp Kraj 134,968,985 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • GO:0001948, GO:0016582 vezivanje za proteine Ćelijska komponenta • citoplazma • jedro • transcription regulator complex Biološki proces • multicellular organism development • Ćelijska diferencijacija • positive regulation of DNA-binding transcription factor activity • nervous system development • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	55859	12069
Ensembl	ENSG00000133169	ENSMUSG00000042750
UniProt	Q9HBH7	Q9WTZ8
RefSeq (mRNK)	NM_018476	NM_009749
RefSeq (bjelančevina)	NP_060946	NP_033879
Lokacija (UCSC)	Chr X: 103.06 – 103.06 Mb	Chr X: 134.97 – 134.97 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Nukleotidna sekvenca (378 nt)

ATGGAGTCCAAAGAGAAA
CGAGCAGTAAACAGTCTCA
GCATGGAAAATGCCAACCA
AGAAAATGAAGAAAAGGAG
CAAGTTGCTAATAAAGGGG
AGCCCTTGGCCCTCCCTTT
GGATGCTGGTGAATACTGT
GTGCCTAGAGGAAATCGTA
GGCGGTTCCGCGTTAGGC
AGCCCATCCTGCAGTATAG
AT GGGATATGATGCATA
GGCTTGGAGAACCACAGG
CAAGGATGAGAGAAGAGA
ATA TGGAAAGGATTGGG
GAGGAGGTGAGACAGCTG
ATGGAAAAGCTGAGGGAA
AAGCAGTTGAGTCATAGT
CTGCGGGCAGTCAGCACT
GACCCCCCTCACCATGAC
CATCATGA TGAGTTTTG
CCTTATGCCCTGA

Translacija (125 aa)

MESKEKRAVNSLSMENAN
QENEEKEQVANKGEPLAL
PLDAGEYCVPRGNRRRFR
VRQPILQYRWDMMHRLG
EPQARMREENMERIGEEV
RQLMEKLREKQLSHSLRA
VSTDPPHHDHHDEFCLMP

Dopunska literatura

• Foltz G; Ryu GY; Yoon JG; et al. (2006). "Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma". Cancer Res. 66 (13): 6665–74. doi:10.1158/0008-5472.CAN-05-4453. PMID 16818640.
• Alvarez E, Zhou W, Witta SE, Freed CR (2005). "Characterization of the Bex gene family in humans, mice, and rats". Gene. 357 (1): 18–28. doi:10.1016/j.gene.2005.05.012. PMID 15958283.
• Quentmeier H; Tonelli R; Geffers R; et al. (2005). "Expression of BEX1 in acute myeloid leukemia with MLL rearrangements". Leukemia. 19 (8): 1488–9. doi:10.1038/sj.leu.2403820. PMID 15920485.
• Baldisseri DM; Margolis JW; Weber DJ; et al. (2002). "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction". J. Mol. Biol. 319 (3): 823–37. doi:10.1016/S0022-2836(02)00282-6. PMID 12054873.
• Yang QS; Xia F; Gu SH; et al. (2002). "Cloning and expression pattern of a spermatogenesis-related gene, BEX1, mapped to chromosome Xq22". Biochem. Genet. 40 (1–2): 1–12. doi:10.1023/A:1014565320998. PMID 11989783.