BEX2

BEX2
Identifikatori
Aliasi	BEX2
Vanjski ID-jevi	OMIM: 300691 MGI: 1338017 HomoloGene: 135604 GeneCards: BEX2
Lokacija gena (čovjek)
Hrom.	Hromosom X
Kraj	103,311,007 bp
Lokacija gena (miš)
Hrom.	Hromosom X (miš)
Kraj	134,968,985 bp
Ontologija gena
Molekularna funkcija	• GO:0001948, GO:0016582 vezivanje za proteine;
Ćelijska komponenta	• citoplazma; • jedro;
Biološki proces	• regulation of apoptotic process; • ćelijski ciklus; • regulation of cell cycle; • GO:0097285 apoptoza;
	Izvori:Amigo / QuickGO
Ortolozi
	84707
	12069
	ENSG00000133134
	ENSMUSG00000042750
	Q9BXY8
	Q9WTZ8
	NM_032621; NM_001168399; NM_001168400; NM_001168401
	NM_009749
	NP_001161871; NP_001161872; NP_001161873; NP_116010
	NP_033879
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein BEX2, znan i kao moždano eksprimirajući X-vezani protein 2 je protein koji je kod ljudi kodiran genom BEX2.^[5]^[6]

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000133134 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000042750 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
^ "Entrez Gene: BEX2 brain expressed X-linked 2".

Dopunska literatura

Baldisseri DM; Margolis JW; Weber DJ; et al. (2002). "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction". J. Mol. Biol. 319 (3): 823–837. doi:10.1016/S0022-2836(02)00282-6. PMID 12054873.
Alvarez E, Zhou W, Witta SE, Freed CR (2005). "Characterization of the Bex gene family in humans, mice, and rats". Gene. 357 (1): 18–28. doi:10.1016/j.gene.2005.05.012. PMID 15958283.
Han C; Liu H; Liu J; et al. (2005). "Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex". Nucleic Acids Res. 33 (20): 6555–6565. doi:10.1093/nar/gki964. PMC 1298925. PMID 16314316.
Foltz G; Ryu GY; Yoon JG; et al. (2006). "Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma". Cancer Res. 66 (13): 6665–6674. doi:10.1158/0008-5472.CAN-05-4453. PMID 16818640.
Fischer C; Drexler HG; Reinhardt J; et al. (2007). "Epigenetic regulation of brain expressed X-linked-2, a marker for acute myeloid leukemia with mixed lineage leukemia rearrangements". Leukemia. 21 (2): 374–377. doi:10.1038/sj.leu.2404493. PMID 17251904.
Naderi A; Teschendorff AE; Beigel J; et al. (2007). "BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines". Cancer Res. 67 (14): 6725–6736. doi:10.1158/0008-5472.CAN-06-4394. PMID 17638883.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000133134 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000042750 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: BEX2 brain expressed X-linked 2".

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