Razlika između verzija stranice "Salicilna kiselina"

▲The medicinal properties of salicylate, mainly for [[fever]] relief, have been known since [[1763|ancient times]], and it was used as an anti-inflammatory drug.<ref>{{cite journal|title=Brief History of Antipyretic Therapy|author=Philip A. Mackowiak|journal=Clinical Infectious Diseases,| volume= 31|year=2000 |pages= 154–156|doi= 10.1086/317510}}</ref>

▲Also known as 2-hydroxybenzoic acid, one of several beta hydroxy acids (compare to [[Alpha hydroxy acid|AHA]]), salicylic acid is a key ingredient in many skin-care products for the treatment of [[Acne vulgaris|acne]], [[psoriasis]], [[callus]]es, [[callus|corns]], [[keratosis pilaris]], and [[wart]]s.<ref>http://www3.interscience.wiley.com/journal/119449119/abstract?CRETRY=1&SRETRY=0</ref> It works as a [[keratolytic]] by causing the cells of the [[Epidermis (skin)|epidermis]] to shed more readily, preventing [[sebaceous gland|pores]] from clogging up, and allowing room for new cell growth. Because of its effect on skin cells, salicylic acid is used in several [[shampoo]]s used to treat [[dandruff]]. Use of concentrated solutions of salicylic acid may cause [[hyperpigmentation]] on unpretreated skin for those with darker skin types ([[Fitzpatrick scale|Fitzpatrick]] phototypes IV, V, VI), as well as with the lack of use of a broad spectrum sunblock.<ref>{{cite journal|title=The Safety and Efficacy of Salicylic Acid Chemical Peels in Darker Racial-ethnic Groups| author= Grimes P.E.|journal= Dermatologic Surgery| volume= 25|year= 1999| pages =18–22 | doi = 10.1046/j.1524-4725.1999.08145.x}}</ref><ref>{{cite journal|title= Chemical peeling in ethnic/dark skin| author= Roberts W. E. |journal=Dermatologic Therapy |volume= 17|issue= 2| pages= 196|year= 2004|doi= 10.1111/j.1396-0296.2004.04020.x}}</ref>