Razlika između verzija stranice "CAPN3"

[nepregledana izmjena][nepregledana izmjena]
Uklonjeni sadržaj Dodani sadržaj
m razne ispravke
Red 1:
{{Infokutija gen}}
'''Kalpain-3''' je [[protein]] koji je kod [[ljudi]] [[kodon|kodirn]] [[gen]]om '''CAPN3'''.<ref name="pmid2555341">{{cite journal | vauthors = Sorimachi H, Imajoh-Ohmi S, Emori Y, Kawasaki H, Ohno S, Minami Y, Suzuki K | title = Molecular cloning of a novel mammalian calcium-dependent protease distinct from both m- and mu-types. Specific expression of the mRNA in skeletal muscle | journal = J. Biol. Chem. | volume = 264 | issue = 33 | pages = 20106–11 | date = Decemberdecembar 1989 | pmid = 2555341 }}</ref><ref name="pmid7720071">{{cite journal | vauthors = Richard I, Broux O, Allamand V, Fougerousse F, Chiannilkulchai N, Bourg N, Brenguier L, Devaud C, Pasturaud P, Roudaut C | title = Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A | journal = Cell | volume = 81 | issue = 1 | pages = 27–40 | date = Maymaj 1995 | pmid = 7720071 | doi = 10.1016/0092-8674(95)90368-2 | doi-access = free }}</ref>
Struktura gena
Richard et al. (1995) pokazali su da gen CAPN3 sadrži 24 [[egzon]]a i da se proteže preko 40 kb.
Red 10:
==Aminokiselinska sekvenca==
Dužina [[polipeptid]]nog lanca je 821 [[aminokiselina]], a [[molekularna masa|molekulska težina]]
94.254 [[dalton (jedinica)|Da]]. <ref name="UniProt">{{cite web|url=http://www.uniprot.org/uniprot/P20807#sequences |title=UniProt, P20807 |accessdate=2021-07access-date=12. 7. 2021}}</ref>
 
:Simboli
Red 65:
== Interakcije ==
 
Pokazano je da CAPN3 [[interakcija protein-protein|komunicira]] sa [[titin]]om. <ref name=pmid9642272>{{cite journal | vauthors = Ono Y, Shimada H, Sorimachi H, Richard I, Saido TC, Beckmann JS, Ishiura S, Suzuki K | title = Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A | journal = J. Biol. Chem. | volume = 273 | issue = 27 | pages = 17073–8 | date = Julyjuli 1998 | pmid = 9642272 | doi = 10.1074/jbc.273.27.17073 | doi-access = free }}</ref><ref name=pmid8537379>{{cite journal | vauthors = Sorimachi H, Kinbara K, Kimura S, Takahashi M, Ishiura S, Sasagawa N, Sorimachi N, Shimada H, Tagawa K, Maruyama K | title = Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence | journal = J. Biol. Chem. | volume = 270 | issue = 52 | pages = 31158–62 | date = Decemberdecembar 1995 | pmid = 8537379 | doi = 10.1074/jbc.270.52.31158 | doi-access = free }}</ref>
 
== Reference ==