Razlika između verzija stranice "Sanfilippov sindrom"
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Flavonoid [[genistein]] smanjuje akumulaciju GAG-a.<ref>{{Cite web |url=http://www.bgo.ug.gda.pl/kbm/dmb/staff/gw.htm |title=Archived copy |access-date=2014-01-07 |archive-url=https://web.archive.org/web/20130621114003/http://www.bgo.ug.gda.pl/kbm/dmb/staff/gw.htm |archive-date=2013-06-21 |url-status=dead }}</ref> Studije na životinjama ''[[in vitro]]'' i klinički eksperimenti sugeriraju da simptomi bolesti mogu biti ublaženi odgovarajućom dozom genisteina.<ref name="Piotrowska-2006">{{Cite journal | last1 = Piotrowska | first1 = E. | last2 = Jakóbkiewicz-Banecka | first2 = J. | last3 = Barańska | first3 = S. | last4 = Tylki-Szymańska | first4 = A. | last5 = Czartoryska | first5 = B. | last6 = Wegrzyn | first6 = A. | last7 = Wegrzyn | first7 = G. | title = Genistein-mediated inhibition of glycosaminoglycan synthesis as a basis for gene expression-targeted isoflavone therapy for mucopolysaccharidoses | journal = European Journal of Human Genetics | volume = 14 | issue = 7 | pages = 846–52 |date=Jul 2006 | doi = 10.1038/sj.ejhg.5201623 | pmid = 16670689 | doi-access = free }}</ref> Uprkos prijavljenim korisnim svojstvima, [[genistein]] takođe ima toksične nuspojave.<ref name="Jin-2007">{{Cite journal | last1 = Jin | first1 = Y. | last2 = Wu | first2 = H. | last3 = Cohen | first3 = EM. | last4 = Wei | first4 = J. | last5 = Jin | first5 = H. | last6 = Prentice | first6 = H. | last7 = Wu | first7 = JY. | title = Genistein and daidzein induce neurotoxicity at high concentrations in primary rat neuronal cultures | journal = J Biomed Sci | volume = 14 | issue = 2 | pages = 275–84 |date=Mar 2007 | doi = 10.1007/s11373-006-9142-2 | pmid = 17245525 }}</ref>
Uspostavljeno je nekoliko grupa za podršku i istraživanje, kako bi se ubrzao razvoj novih tretmana Sanfilippovog sindroma.<ref>[https://CureSanfilippoFoundation.org/ Cure Sanfilippo Foundation], funding research to accelerate discovery of a cure to Sanfilippo Syndrome</ref><ref>[http://jonahsjustbegun.org/ Jonah's Just Begun - Foundation to Cure Sanfilippo, Inc.]</ref><ref>[http://phoenixnestbiotech.com/ Phoenix Nest, Inc.], a biotech company seeking treatments and cures for Sanfilippo Syndrome</ref><ref>[http://www.phunkphenomenon.com/the-crews/ Phunk Phenomenon HipHop For Hope] {{Webarchive|url=https://web.archive.org/web/20180901061353/http://www.phunkphenomenon.com/the-crews/ |date=1. 9. 2018 }}, a dance crew in Boston raising awareness for Sanfilippo Syndrome</ref>
<ref>[http://www.teamsanfilippo.org/ Team Sanfilippo Foundation], a medical research foundation created by parents of children with Sanfilippo Syndrome</ref>
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