Podjedinica augminolikog kompleksa HAUS , znana i kao HAUS6 , je ljudski gen .[4]
Aminokiselinska sekvenca
uredi
Dužina polipeptidnog lanca je 955 aminokiselina , а molekulska težina 108.621 Da .[5]
10 20 30 40 50 MSSASVTAFE KEHLWMYLQA LGFEPGPATI ACGKIVSHTH LGVNMFDKLN RDAFHIISYF LFQVLDQSLT KEVFKFCWPP FDQKSDTEFR KHCCEWIKRI SGECGSSFPQ VVGSLFLSPG GPKFIHLMYH FARFVAMKYI KSNSKNSSHH FVETFNIKPQ DLHKCIARCH FARSRFLQIL QRQDCVTQKY QENAQLSVKQ VRNLRSECIG LENQIKKMEP YDDHSNMEEK IQKVRSLWAS VNETLMFLEK EREVVSSVLS LVNQYALDGT NVAINIPRLL LDKIEKQMFQ LHIGNVYEAG KLNLLTVIQL LNEVLKVMKY ERCQADQARL TVDLHYLEKE TKFQKERLSD LKHMRYRIKD DLTTIRHSVV EKQGEWHKKW KEFLGLSPFS LIKGWTPSVD LLPPMSPLSF DPASEEVYAK SILCQYPASL PDAHKQHNQE NGCRGDSDTL GALHDLANSP ASFLSQSVSS SDRNSVTVLE KDTKMGTPKE KNEAISKKIP EFEVENSPLS DVAKNTESSA FGGSLPAKKS DPFQKEQDHL VEEVARAVLS DSPQLSEGKE IKLEELIDSL GSNPFLTRNQ IPRTPENLIT EIRSSWRKAI EMEENRTKEP IQMDAEHREV LPESLPVLHN QREFSMADFL LETTVSDFGQ SHLTEEKVIS DCECVPQKHV LTSHIDEPPT QNQSDLLNKK VICKQDLECL AFTKLSETSR METFSPAVGN RIDVMGGSEE EFMKILDHLE VSCNKPSTNK TMLWNSFQIS SGISSKSFKD NDFGILHETL PEEVGHLSFN SSSSSEANFK LEPNSPMHGG TLLEDVVGGR QTTPESDFNL QALRSRYEAL KKSLSKKREE SYLSNSQTPE RHKPELSPTP QNVQTDDTLN FLDTCDLHTE HIKPSLRTSI GERKRSLSPL IKFSPVEQRL RTTIACSLGE LPNLKEEDIL NKSLDAKEPP SDLTR
Dopunska literatura
uredi
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . 138 (1–2): 171–4. doi :10.1016/0378-1119(94)90802-8 . PMID 8125298 . Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . 200 (1–2): 149–56. doi :10.1016/S0378-1119(97)00411-3 . PMID 9373149 . Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 7 (4): 273–81. doi :10.1093/dnares/7.4.271 PMID 10997877 . Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination" . Genome Res . 10 (11): 1788–95. doi :10.1101/gr.143000 . PMC 310948 PMID 11076863 . Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 PMID 11230166 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9" . Nature . 429 (6990): 369–74. Bibcode :2004Natur.429..369H . doi :10.1038/nature02465 . PMC 2734081 PMID 15164053 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline" . Genome Res . 14 (10B): 2136–44. doi :10.1101/gr.2576704 . PMC 528930 PMID 15489336 . Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006" . Nucleic Acids Res . 34 (Database issue): D415–8. doi :10.1093/nar/gkj139 . PMC 1347501 PMID 16381901 . Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle" . Proc. Natl. Acad. Sci. U.S.A . 103 (14): 5391–6. Bibcode :2006PNAS..103.5391N . doi :10.1073/pnas.0507066103 PMC 1459365 PMID 16565220 . Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization" . Nat. Biotechnol . 24 (10): 1285–92. doi :10.1038/nbt1240 . PMID 16964243 . S2CID 14294292 . 
