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Datoteka:Extrinsic and intrinsic pathways to caspase-3 activation.jpg

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Opis
Čeština: Vnitřní a vnější cesty aktivace kaspázy 3: DISC (death-inducing signaling complex), MAC (mitochondrial apoptosis-induced channel) a apoptosom
English: Figure 1. Extrinsic and intrinsic pathways to caspase-3 activation. Overview of pathways to caspase-3 activation. Each separate gray region represent the three modules: DISC (death-inducing signaling complex), MAC (mitochondrial apoptosis-induced channel) and apoptosome. Species and their symbols are: FasL (FasL), FasR (FasR), DISC (DISC), procaspase-8 and caspase-8 (Casp8), bifunctional apoptosis inhibitor (BAR), procaspase-3 and caspase-3 (Casp3), XIAP (XIAP), Bid and truncated Bid (Bid), Bax (Bax), tBid - Bax2 complex (tBid - Bax2), Smac (Smac), Apaf-1 (Apaf), cytochrome c (Cytc), apoptosome (Apop), procaspase-9 and caspase-9 (Casp9). Arrows denote chemical conversions or catalyzed reactions while hammerheads represent inhibition.
Datum
Izvor Construction and analysis of a modular model of caspase activation in apoptosis
Autor Harrington HA, Ho KL, Ghosh S, Tung KC
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© 2008 Harrington et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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trenutno12:30, 13 septembar 2009Smanjeni pregled verzije na dan 12:30, 13 septembar 20091.200 × 984 (89 KB)CopperKettle{{Information |Description={{en|1=Figure 1. Extrinsic and intrinsic pathways to caspase-3 activation. Overview of pathways to caspase-3 activation. Each separate gray region represent the three modules: DISC (death-inducing signaling complex), MAC (mitoch

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